Synthesis and exploration of a novel chlorobenzylated 2-aminothiazole-phenyltriazole hybrid as migratory inhibitor of B16F10 in melanoma cells.

In the study presented here, a novel chlorobenzylated bi-heterocyclic hybrid molecule () was synthesized and its structural confirmation was carried out by IR, H-NMR, C-NMR and CHN analysis data. This compound was subjected to biological study with B16F10 mouse melanoma cells. The anti-proliferative results showed that showed no significant toxicity at concentrations ranging of 0-44 μM.