Publications by authors named "Syed Ameen Ahmad"
Background: Little is known about quality of life, sleep, and mental health in children with moyamoya arteriopathy (MMA). A better understanding of patient-reported outcomes may lead to improved treatment.
Methods: Patients with MMA <26 years old and their caretakers completed validated, age-appropriate questionnaires including the Pediatric Quality of Life (PedsQL) Inventory and Patient-Reported Outcomes Measurement Information System (PROMIS) measuring health-related quality of life, sleep, anxiety, depression, and overall health.
Background: In this COVID-19 Critical Care Consortium (CCCC) sub-study, we qualified neurological complications associated with SARS-CoV2 infection.
Methods: The CCCC is an international, multicenter study. Eligible patients were COVID-19 patients admitted to intensive care units (ICU) across 23 centers between 1/7/2020 to 6/23/2022.
Objective: CT hyper-perfusion has been reported in non-convulsive status epilepticus (NCSE), while its occurrence and relevance after single seizures or with rhythmic and periodic patterns (RPPs) that lie along the ictal-interictal continuum (IIC), remain unclear. The goal of the study is to assess the role of CT perfusion (CTP) in diagnosing patients with clinical seizures, subclinical seizures, or RPPs that lie along the IIC, to help in the clinical assessment of these entities.
Methods: We retrospectively reviewed inpatients who underwent a CTP and an EEG within 6 h of each other.
Article Synopsis
- The study analyzes sex differences in ICU outcomes for severe COVID-19 patients, focusing on mortality rates between males and females.
- It includes data from 10,259 patients admitted to ICUs worldwide between January 2020 and June 2022, revealing that males had a higher hazard of death (HR=1.14) despite adjustment for complications.
- Additionally, males exhibited more severe health issues, requiring greater interventions and showing higher risks for cardiac arrest and pulmonary embolism compared to females.
Introduction: Early diagnosis of acute brain injury (ABI) is critical for patients on veno-arterial extracorporeal membrane oxygenation (V-A ECMO) to guide anticoagulation strategy; however, neurological assessment in ECMO is often limited by patient sedation.
Methods: In this pilot study of adults from June 2018 to May 2019, plasma samples of glial fibrillary acidic protein (GFAP), neurofilament light chain (NFL), and tubulin associated unit (Tau) were collected daily after V-A ECMO cannulation and measured using a multiplex platform. Primary outcomes were occurrence of ABI, assessed clinically, and neurologic outcome, assessed by modified Rankin Scale (mRS).
Background: Children with moyamoya are at high risk for incident and recurrent stroke. Transcranial Doppler (TCD) ultrasound is an attractive option to screen high-risk populations for moyamoya and to provide stroke risk stratification information due to its safety and cost-effectiveness. We used TCD to evaluate cerebral blood flow velocities in children with presurgical moyamoya and to determine if velocities differ between children with stable and unstable disease.
View Article and Find Full Text PDFRelative anemia and perioperative stroke in children with moyamoya.
J Stroke Cerebrovasc Dis
January 2024
Objectives: Surgical revascularization for moyamoya arteriopathy decreases long-term stroke risk but carries a risk of perioperative ischemic complications. We aimed to evaluate modifiable stroke risk factors in children undergoing surgical revascularization for moyamoya.
Materials And Methods: In this exploratory, single-center, retrospective cohort study, medical records of pediatric patients undergoing surgical revascularization for moyamoya arteriopathy at our center between 2003 and 2021 were reviewed.
Background: Despite the high prevalence of neurological complications and mortality associated with extracorporeal cardiopulmonary resuscitation (ECPR), neurologically-focused animal models are scarce. Our objective is to review current ECPR models investigating neurological outcomes and identify key elements for a recommended model.
Methods: We searched PubMed and four other engines for animal ECPR studies examining neurological outcomes.
Background: Children with moyamoya arteriopathy are at high risk for stroke and seizures. Risk factors for seizures and the impact of seizures on neurological outcomes in children with moyamoya are unknown.
Methods: This is a single-center retrospective cohort study of children with moyamoya evaluated between 2003 and 2021.
Article Synopsis
- * The exact causes of these symptoms are not fully understood, but theories involve persistent viral presence, immune system dysfunction, and blood vessel issues that affect the brain and nervous system.
- * Current treatments aim to address these mechanisms by using antivirals, reducing inflammation, and supporting the recovery of sensory functions like smell.