Publications by authors named "Sye Lim Hong"
Background: Though observational evidence supports indirect effects of SARS-CoV-2 vaccines, randomised experiments are lacking. To address this gap, the double-blinded, prospective follow-up of the household contacts (HHCs) of Philippine participants of the individually-randomised, placebo-controlled trial of the adjuvanted-subunit protein COVID-19 vaccine, SCB-2019, (EudraCT, 2020-004272-17; ClinicalTrials.gov, NCT04672395) was analyzed in a cluster-randomised fashion.
View Article and Find Full Text PDFSARS-CoV-2 serological testing is useful to determine seroprevalence, epidemiological trends, and the extent of transmission. The collection and transport of serum samples can be logistically challenging, especially in remote underserved areas. Dried blood spots (DBSs) would allow easier sample collection and logistical handling compared with standard serum collection, particularly for extensive and repeated SARS-CoV-2 serosurveys.
View Article and Find Full Text PDFArticle Synopsis
- This study aimed to evaluate the effectiveness of bivalent versus monovalent COVID-19 vaccines during the 2022-2023 winter using real-world data from South Korea.
- The research included 29,245 adults and found that bivalent vaccine recipients had a 12.2% higher protection against COVID-19 compared to those receiving the monovalent vaccine, especially noted at 39.4% for individuals in long-term care facilities.
- The study concludes that bivalent vaccines offer superior protection, suggesting they should be prioritized in immunization programs to combat seasonal COVID-19 outbreaks.