Immunoglobulins and their use in children.

Immunoglobulin preparations are one of the products of the human plasma fractionation, where the plasma is obtained, in accordance with WHO guidelines from at least 1,000 donors. These preparations contain all IgG subclasses with various antigen characteristics. In clinical practice these drugs are used as replacement therapy in patients with primary and secondary immunodeficiencies as well as immunomodulatory therapy in many autoimmune diseases and systemic inflammatory diseases.

Identification and characterization of acute infection with parvovirus B19 genotype 2 in immunocompromised patients in Poland.

Parvovirus B19 (B19V) is divided into three genotypes. Genotypes 2 and 3 may cause diagnostic difficulties and their epidemiology is not well understood. In the present study the prevalence of B19V genotypes in patients with symptomatic infection in Poland was evaluated and the course of infection in patients infected with non-genotype 1 strains is described.

[Erythropoietin treatment of infants with anaemia in the first three months of life].

Unlabelled: Synthesis of recombinant human erythropoietin opened new possibilities for treatment of anaemia in infants.

Aim: To assess the safety and effects of this treatment of anaemia in infants.

Material And Methods: The study included 111 infants with anaemia aged between 3 and 10 weeks.

[Danazol - effective second line therapy in idiopathic thrombocytopenic purpura in children. Three case reports].

Danazol is an accredited second line drug for idiopathic thrombocytopenic purpura (ITP) in adults. There are very few positions in the literature about using danazol in children, although some articles quote its evident efficacy. In this paper we present three cases of children treated with danazol.