Cluster EK2 Akoni, Ashton, and Truong are lytic actinobacteriophages that were isolated from soil in Florida using Microbacterium foliorum NRRL B-24224 as the host. The genomes are 54,307 bp, 54,560 bp, and 54,309 bp, respectively, and are 60% GC rich. Each genome contains a novel 13,464-bp gene that encompasses 25% of the genome.
View Article and Find Full Text PDFThe ATP-sensitive P2X ionotropic receptor plays a critical role in a number of signal processes including taste and hearing, carotid body detection of hypoxia, the exercise pressor reflex and sensory transduction of mechanical stimuli in the airways and bladder. Elucidation of the role of P2X has been hindered by the lack of selective tools. In particular, detection of P2X using established pharmacological and biochemical techniques yields dramatically different expression patterns, particularly in the peripheral and central nervous systems.
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