Dual behavior of N-acetylcysteine during ethanol-induced oxidative stress in embryonic chick brains.

Objectives: Ethanol (EtOH) causes oxidative stress in embryos. Because N-acetylcysteine (NAC) failures and successes in ameliorating EtOH-induced oxidative stress have been reported, the objective was to determine if exogenous NAC ameliorated EtOH-induced oxidative stress within embryonic chick brains.

Methods: Control eggs were injected with approximately 25 µl of water on day 0, 1, and 2 of development (E).