Response of protein S100B to playing American football, lifting weights, and treadmill running.

Objective: To determine if serum S100B increases similarly as a result of playing American football compared to exercise alone.

Methods: Serum S100B was measured in division III collegiate football players before and after every home game during a single football season. Serum S100B was also measured before and after subjects walked on a treadmill for 30 minutes at a leisurely pace, ran on a treadmill while wearing and not wearing a football helmet at 6 mph for 8 minutes, and performed low-, moderate-, or high-intensity resistance exercise.