Delayed cord clamping in South African neonates with expected low birthweight: a randomised controlled trial.

Objective: To evaluate safety and haematological effects of delayed cord clamping (DCC) in infants with expected low birthweight born in a resource-poor setting.

Methods: Randomised controlled trial involving pregnant women in early labour ≥18 years with intrapartum symphysal-fundal height ≤32 cm. Mothers were randomised for either early cord clamping (ECC, <30 s) or DCC (2-3 min after birth).

Vibrating membrane devices deliver aerosols more efficient than standard devices: a study in a neonatal upper airway model.

Background: Aerosol therapy in preterm infants is challenging, as a very small proportion of the drug deposits in the lungs.

Aim: Our aim was to compare efficiency of standard devices with newer, more efficient aerosol delivery devices.

Methods: Using salbutamol as a drug marker, we studied two prototypes of the investigational eFlow(®) nebulizer for babies (PARI Pharma GmbH), a jet nebulizer (Intersurgical(®) Cirrus(®)), and a pressurized metered dose inhaler (pMDI; GSK) with a detergent-coated holding chamber (AeroChamber(®) MV) in the premature infant nose throat-model (PrINT-model) of a 32-week preterm infant (1,750 g).

[A neonate without claviculae].

A 1-week-old girl, term born after a non-complicated parturition, presented with abnormal clavicles. At physical examination small and short clavicles were seen, as well as a widened anterior and posterior fontanelle. An X-ray of the thorax showed hypoplastic clavicles and an X-ray of the skull showed delayed ossification of the bones, hypoplasia of the maxilla and extra teeth.