Publications by authors named "Syawal Abdurrahman"
Article Synopsis
- * Research suggests that henna plant's phenolic compounds, particularly luteolin, can act as an anti-diabetic agent by inhibiting the α-amylase enzyme, which is crucial for sugar digestion.
- * Molecular studies revealed that luteolin shows strong binding interactions with α-amylase and α-glucosidase, indicating its potential effectiveness in diabetes treatment, with favorable characteristics for absorption and stability in the body. *
Alopecia is a condition in which hair on the scalp or other areas of the body is lost or falls out excessively. Nutritional deficiency causes blood flow to the head to decrease causing the hormone testosterone to be changed by the enzyme 5-α-reductase to dihydrotestosterone, which inhibits the growth phase and accelerates the death phase. One of the methods developed to treat alopecia is through inhibition of the 5-α-reductase enzyme, which converts testosterone to its more potent metabolite, dihydrotestosterone (DHT).
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- Alopecia is a condition characterized by hair loss due to a mix of genetic, environmental, and nutritional factors, with treatments targeting the enzyme 5-alpha reductase to block the formation of a potent hormone linked to hair loss.
- An in vivo study on rabbits tested the antialopecia effects of ethanolic extracts from a specific plant, revealing that certain fractions (F2 and F3) significantly promoted hair growth, outperforming a control treatment (minoxidil).
- Analysis identified bufotalinin, a compound from the plant, as a strong potential treatment due to its effective binding to androgen receptors and favorable absorption properties, suggesting it could serve as an alternative therapy for hair loss.
The target for COVID-19 has been successfully crystallized along with its inhibitor, named SARS-CoV-2 main protease, making it easier for drug discovery and development. Sponge ( Sp.) is a marine species that can be found in Indonesia and has a unique chemical structure that is still rarely explored in its properties.
View Article and Find Full Text PDFAlopecia is a condition in which some or all of the hair from the scalp is lost. One recent preventative measure is the inhibition of the enzyme 5-α-reductase. Inhibition of the enzyme 5-α-reductase converts circulating testosterone to its more potent metabolite, dihydrotestosterone.
View Article and Find Full Text PDFThree new 5,6-dihydro-α-pyrones derivatives, named (S)-rugulactone (1) pulchrinervialactone A (2), and pulchrinervialactone B (4), along with one known pyrone, cryptobrachytone C (3), and three known amide derivatives (5-7) have been isolated from the leaves of Cryptocarya pulchrinervia. The structures of 1-7 were elucidated based on extensive spectroscopic data and comparison with literatures. The configurations of compounds 3 and 4 were established by single crystal X-ray diffraction analysis.
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