Publications by authors named "SyahrulAzlin Shaari"
Drug Metab Pharmacokinet
August 2016
Article Synopsis
- A study characterized CYP2C9 gene variants in 61 Orang Asli and 96 Singaporean Malays using whole genome sequencing and compared these with 11 other populations.
- The Orang Asli showed the highest frequency of the CYP2C9*3 variant and had three clinically significant alleles, suggesting they might need lower drug doses due to reduced metabolic capacity.
- The findings highlighted differences in genetic patterns among populations and underscored the importance of understanding genetic variations for better precision medicine in the Orang Asli.
