Quantitative determination of the antibacterial activity of licorice (Glycyrrhiza glabra) and tetracycline gel against (Aa), (Pg) and (Pi) - a microbiological study.

Objectives: The aim of this study was to evaluate and compare the antibacterial efficacy of licorice gel and tetracycline gel against , and .

Methods: An indigenously prepared 50 μL licorice and tetracycline gel was subjected to antibacterial sensitivity test (thrice) against Aa, Pg, Pi by agar well diffusion method using Brain Heart Infusion media. Colonies of Aa, Pg, Pi was transferred into broth and incubated at 37 °C for 24 h and diameter of inhibition zone was measured.

Predictors for multidrug-resistant organisms (MDROs) carriage in haemodialysis patients.

Introduction: Infections in haemodialysis (HD) patients are an important cause of morbidity, hospitalization, and mortality. Patients undergoing HD are more prone to develop bacterial infections by multidrug-resistant organisms (MDROs).

Objectives: This study is aimed to detect MDROs colonization in HD patients and its associated risk factors and outcome.

Nitrogen-doped carbon dots: Recent developments in its fluorescent sensor applications.

Doped carbon dots have attracted great attention from researchers across disciplines because of their unique characteristics, such as their low toxicity, physiochemical stability, photostability, and outstanding biocompatibility. Nitrogen is one of the most commonly used elements for doping because of its sizeable atomic radius, strong electronegativity, abundance, and availability of electrons. This distinguishes them from other atoms and allows them to perform distinctive roles in various applications.

Hypoglycemic Potential of in Liver Is Mediated through IRS-2/PI3K/SREBP-1c/GLUT2 Signaling in High-Fat-Diet-Induced Type-2 Diabetic Male Rats.

Regardless of socioeconomic or demographic background, the prevalence of type 2 diabetes mellitus, which affects more than half a billion people worldwide, has been steadily increasing over time. The health, emotional, sociological, and economic well-being of people would suffer if this number is not successfully handled. The liver is one of the key organs accountable for sustaining metabolic balance.

Comprehensive analysis of non-synonymous missense SNPs of human galactose mutarotase (GALM) gene: an integrated computational approach.

Missense Non-synonymous single nucleotide polymorphisms (nsSNPs) of Galactose Mutarotase (GALM) are associated with the Novel type of Galactosemia (Galactosemia type 4) together with symptoms such as high blood galactose levels and eye cataracts. The objective of the present study was to identify deleterious nsSNPs of GALM recorded on the dbSNP database through comprehensive analysis. Among the 319 missense nsSNPs reported, various tools predicted R78S, R82G, A163E, P210S, Y281C, E307G and F339C as the most deleterious mutations.

Managing the triad of triple mullerian anomaly, endometriosis and adenomyosis - A case report.

Introduction And Importance: Report of an extremely rare case of triple Mullerian anomaly consisting of cervical agenesis, partial vaginal agenesis and complete bicorporeal uterus with functioning endometrium associated with adenomyosis and pelvic endometriosis in a young girl managed with hysterectomy of both uterine horns and excision of pelvic endometriosis.

Presentation Of Case: A 20-year-old young woman presented with primary amenorrhoea and severe cyclical pain abdomen. She was diagnosed with a rare triple Mullerian anomaly consisting of cervical agenesis, partial vaginal agenesis and complete bicorporeal uterus with functioning endometrium associated with adenomyosis and pelvic endometriosis.

Nested Real-Time PCR Assessment of Vertical Transmission of Sandalwood Spike Phytoplasma ('. Phytoplasma asteris').

The Sandalwood Spike disease (SSD)-related to '. Phytoplasma asteris' has threatened the existence of sandalwood in India. The epidemiology of SSD is still poorly understood despite the efforts to understand the involvement of insect vectors in SSD transmission and alternate plant hosts over the last two decades.

Recurrent perineal scar endometriosis: A case report.

Introduction: Endometriosis is a chronic disease with the presence of endometrium-like tissue containing endometrial glands and stroma outside the uterus. The incidence of episiotomy scar endometriosis after vaginal delivery is 0.06-0.

Optimization of an all-optical three-input universal logic gate with an enhanced contrast ratio by exploiting a T-shaped photonic crystal waveguide.

Universal gates (NAND and NOR) are used for any electronic circuit that is affordable and straightforward to build all logic gates (LoG). In this work, the T-shaped 2D photonic crystal (PhC) is exploited to design a three-input universal LoG premised on the beam-interference principle. The design criteria of pitch (), rod radius (), and refractive index () are employed to obtain a high impact output.

Ni/Ni(OH)-rGO nanocomposites sensor for the detection of long forgotten mycotoxin, xanthomegnin.

Xanthomegnin, a known fungal toxin, secondary metabolite, and pigment diffuses from the dermatophytes has gained attention as local virulence factor because of the mutagenicity, toxicity, cytocidal, and immunosuppressive properties. Not only as a dermatophyte in skin related disorders, the production of xanthomegnin is implicated as a powerful diagnostic marker in patients suffering from ocular mycoses. Incidentally also attributed to death in livestock's majorly by exposing themselves to food-borne fungi like Aspergillus and Penicillium.

Rothia santali sp. nov., endophytic bacteria isolated from sandalwood (Santalum album L.) seedling.

A novel, mustard yellow-pigmented aerobic bacterial strain designated AR01 was isolated from hypocotyl tissue of a sandalwood seedling from Bangalore, India. The 16S rRNA gene of strain AR01 had the highest 98.97% sequence similarity with Rothia halotolerans YIM 90716 (KCTC 19172) followed by Rothia kristinae PM 129 (NBRC 15354) (97.

A case of didelphys uterus: tackling the double trouble adenomyosis and infertility.

Objective: To present a case of didelphys uterus with severe pelvic pain and primary infertility with focal adenomyosis of outer myometrium (FOAM) of the left hemiuterus and tips and tricks for hemihysterectomy as a fertility preserving surgery.

Design: Descriptive step-by-step video demonstration of a case of didelphys uterus with adenomyosis of the hemiuterus. Local institutional review board approval for publication was obtained.

Primary Umbilical endometriosis - case series and review of clinical presentation, diagnosis and management.

Introduction: Umbilical endometriosis is the most common cutaneous form and is seen mostly secondary to surgical scar and rarely occurs as primary umbilical endometriosis. The objective of this retrospective case series evaluation is to report the presentation, diagnosis, and management of patients with primary umbilical endometriosis.

Presentation Of Cases: We present a retrospective, observational and descriptive review of cases presenting with primary umbilical endometriosis among Indian women managed in two private tertiary care centres between 2018 and 2020.

Immunohistochemical evaluation of survivin in oral lichen planus and oral squamous cell carcinoma - a retrospective study.

Introduction: Oral cancer is a multistep process involving enhanced activation of proto-oncogenes. Survivin (anti-apoptotic protein) is one of such proto-oncogenes that contribute to the carcinogenesis by deregulating cell proliferation. Expression of these proteins in cancerous and pre-cancerous lesions helps a better understanding of the etiology, treatment and prognosis.

A Needle in the Fetal Brain: The Rare Role of Transabdominal Cephalocentesis in Fetal Hydrocephalus.

Fetal hydrocephalus is a fairly common occurrence in pregnant women, surfacing early or late in the pregnancy. The perinatal and pediatric outcomes are largely determined by the cause of hydrocephalus and the extent of the irreversible destruction of the brain tissue. In pregnancies where the fetal prognosis is unfavorable, aspirating the cerebrospinal fluid (CSF) to facilitate vaginal delivery is an option.

The Association Between Ferritin and Vitamin D Levels in Premenopausal Fibroid Uterus Cases With Anemia.

Objective The present study aimed to evaluate the association between serum ferritin and vitamin D levels in fibroid uterus cases presenting with anemia. Methods Sixty premenopausal women with uterine fibroids (30 associated with anemia and 30 without anemia) were enrolled as cases and control. All participants were evaluated on the basis of a questionnaire, which included queries related to obstetric, medical, and sociodemographic history.

Genetically encoded light-up RNA aptamers and their applications for imaging and biosensing.

Intracellular small ligands and biomacromolecules are playing crucial roles not only as executors but also as regulators. It is essential to develop tools to investigate their dynamics to interrogate their functions and reflect the cellular status. Light-up RNA aptamers are RNA sequences that can bind with their cognate nonfluorescent fluorogens and greatly activate their fluorescence.

Estimation of superoxide dismutase levels in saliva and gingival crevicular fluid among smokers and non-smokers in periodontitis patients - An Observational Study.

Background: Smoking, which is an important risk factor for periodontitis, induces oxidative stress in the body and causes an imbalance between reactive oxygen species (ROS) and antioxidants, such as superoxide dismutase (SOD). The present study was done to quantify and compare the level of SOD enzyme levels in gingival crevicular fluid (GCF) and saliva among smokers and nonsmokers.

Methodology: One hundred and thirty-five individuals in the age range of 20-55 years, including 45 light smokers, 45 heavy smokers, and 45 nonsmokers (controls), were selected and the clinical parameters recorded were plaque index, probing depth, and attachment loss.

Nanomaterial-Enabled Wearable Sensors for Healthcare.

Highly sensitive wearable sensors that can be conformably attached to human skin or integrated with textiles to monitor the physiological parameters of human body or the surrounding environment have garnered tremendous interest. Owing to the large surface area and outstanding material properties, nanomaterials are promising building blocks for wearable sensors. Recent advances in the nanomaterial-enabled wearable sensors including temperature, electrophysiological, strain, tactile, electrochemical, and environmental sensors are presented in this review.

Expression of inducible nitric oxide synthase in the epithelial linings of odontogenic keratocyst, dentigerous cyst and radicular cyst: a pathological insight.

Background: The present study is aimed at analyzing the expression of inducible nitric oxide synthase (iNOS) in the epithelial lining of odontogenic keratocyst (OKC), dentigerous cyst (DC), radicular cyst (RC) in order to understand the possible role of iNOS with special reference to its neoplastic nature and local aggressive of cysts.

Aim: The primary aim of the following study is to analyze the immunohistochemical expression of iNOS and secondary aim is to compare the iNOS expression, pattern and intensity of staining among the epithelial linings of OKC, DC and RC.

Materials And Methods: iNOS in the epithelial lining cells were analyzing in 10 OKC's, 10 DC's and 10 RC's using immunohistochemistry.

Report of a rare case of an odontogenic myxoma of the maxilla and review of literature.

Odontogenic myxoma (OM) is a mesenchymal tissue benign neoplasia, being relatively rare which is almost exclusively seen in tooth-bearing areas. OM commonly occurs in the 2(nd) and 3(rd) decade and the mandible is involved more commonly than the maxilla. The lesion often grows without symptoms and presents as a painless swelling.

Assessment of thickness of palatal masticatory mucosa and maximum graft dimensions at palatal vault associated with age and gender - a clinical study.

Background: Periodontitis is a multifactorial inflammatory disease which leads to alveolar bone loss, followed by exposure of root surfaces, which results in an unaesthetic appearance. Palatal masticatory mucosa is widely used as a donor tissue for root coverage procedures, to achieve an aesthetic appearance and to meet patient's needs. Obtaining sufficient volume of tissue without injuring the vessels is necessary.

Characterization of different verrucous mucosal lesions.

Oral lesions indicative of biopsy represent unique presentation either in the form of proliferations/ulcerations of the squamous lining epithelium. These lesions have similar appearance clinically and histopathologically hence are excised for microscopic evaluation to rule out early or hidden malignancy. Verrucous mucosal lesions clinically present a diagnostic dilemma, which makes histopathological examination a significant one in the differentiation of the lesion to ascertain the nature.

Selective electrochemical recognition of the α-naphthol isomer and in situ immobilization of naphthoquinones for tunable electrocatalysis.

Fits like a glove: Separationless and selective electrochemical oxidation of the α-naphthol (α-NAP) isomer yields naphthoquinone species on the surface of multiwalled carbon nanotubes, which can further catalyze the electro-oxidation of NADH and hydrazine at different potentials. The β-NAP isomer failed to show any such electro-oxidation.