Applications and advancements of polysaccharide-based nanostructures for enhanced drug delivery.

Growing demand for highly effective, site-specific delivery of pharmaceuticals and nutraceuticals using nano-sized carriers has prompted increased scrutiny of carrier biocompatibility and biodegradability. To address these concerns, biodegradable natural polymers have emerged as a transformative domain, offering non-toxic, precisely targetable carriers capable of finely modulating cargo pharmacokinetics while generating innocuous decomposition by-products. This comprehensive review illuminates the emergence of polysaccharide-based nanoparticulate drug delivery systems.

Magnetically controlled release of cisplatin from superparamagnetic starch nanoparticles.

The present study involves a novel strategy for the preparation of superparamagnetic nanoparticles of crosslinked starch impregnated with homogeneously dispersed nanosized iron oxide. The nanoparticles were loaded with an anticancer drug 'cisplatin' and the drug release kinetics was investigated spectrophotometrically at physiological pH (7.4).