An Unusual Case of Pancytopenia.

Multiple myeloma is a rare hematological disorder that causes overproduction of plasma cells within the bone marrow, leading to suppressed hematopoiesis, renal insufficiency, bony lesions, and recurrent infections. Patients with multiple myeloma commonly present with anemia. Although rare, neutropenia and thrombocytopenia can also develop in these patients, leading to pancytopenia, as seen in our case.

A study of modified Wells score for pulmonary embolism and age-adjusted D-dimer values in patients at risk for deep venous thrombosis.

Aims: Pulmonary embolism (PE) is the most severe complication of deep venous thrombosis (DVT). This study was designed to evaluate the usefulness of modified Wells score combined with age-adjusted D-dimer cut-off levels as a clinical pre-test probability assessment for predicting PE in patients 'at risk for DVT.'

Methods: This was a cross-sectional study including 200 in-patients at risk for DVT.

Impact of Dental Treatment on Oral Health-Related Quality of Life of Patients.

Objective: It is crucial to understand how individuals perceive the impact of oral disorders and the treatment associated with or received for those disorders on their quality of life. A relatively new but quickly spreading concept of oral health-related quality of life (OHRQoL) that notably affects three fields, clinical dental practice, dental research, and dental education makes it feasible to figure out the relationship between oral health and its impact on the quality of life of an individual. OHRQoL can be measured in various ways; the most well-liked method uses a multiple-item questionnaire.

A hospital-based study on the prevalence of trichomoniasis and evaluation of accuracy of various diagnostic techniques.

Background: The sexually transmitted infections (STIs) caused by have been associated with adverse pregnancy outcomes and increased risk of HIV transmission. Trichomoniasis remains underreported despite being easy to diagnose and treat. Moreover, availability of battery of diagnostic tools causes dilemma on the most appropriate techniques to be used.

Aerobic vaginitis - An underdiagnosed cause of vaginal discharge - Narrative review.

The concept of vaginal dysbiosis was for long considered synonymous with bacterial vaginosis (BV), which is characterized by a homogenous non-inflammatory vaginal discharge. The inflammatory variant of vaginal dysbiosis, called aerobic vaginitis (AV), has remained unknown to a large part of the global dermatology and venereology community, gynaecologists and reproductive tract infection specialists with consequential under diagnosis. AV significantly differs from BV, in clinical presentation, diagnostic criteria and management.

Electronic Nature of Neutral and Charged Two-Photon Absorbing Squaraines for Fluorescence Bioimaging Application.

The electronic properties of neutral 2,4-bis(4-bis(2-hydroxyethyl) amino-2-hydroxy-6-(2-(2-(2-methoxyethoxy)ethoxy)ethoxy)phenyl)squaraine () and charged 2-((3-octadecylbenzothiazol-2(3)-ylidene)methyl)-3-oxo-4-((3-(4-(pyridinium-1-yl)butyl)benzo-thiazol-3-ium-2-yl)methylene)cyclobut-1-enolate iodide () squaraine derivatives were analyzed based on comprehensive linear photophysical, photochemical, nonlinear optical studies (including two-photon absorption (2PA) and femtosecond transient absorption spectroscopy measurements), and quantum chemical calculations. The steady-state absorption, fluorescence, and excitation anisotropy spectra of these new squaraines revealed the values and mutual orientations of the main transition dipoles of and in solvents of different polarity, while their role in specific nonlinear optical properties was shown. The degenerate 2PA spectra of and exhibited similar shapes, with maximum cross sections of ∼300-400 GM, which were determined by the open aperture -scan method over a broad spectral range.

Mitochondria Penetrating Peptide-Conjugated TAMRA for Live-Cell Long-Term Tracking.

Mitochondria are essential targets for treatment of diseases with mitochondrial disorders such as diabetes, cancer, and cardiovascular and neurodegenerative diseases. Mitochondria penetrating peptides (MPPs) are composed of cationic and hydrophobic amino acids that can target and permeate the mitochondrial membrane. Herein, a novel d-argine-phenylalanine-d-argine-phenylalanine-d-argine-phenylalanine-NH (rFrFrF) was tagged with a rhodamine-based fluorescent chromophore (TAMRA).

Impact of environmental changes on the reproductive biology in Pyrostegia venusta Presl.

Local environment (temperature and relative humidity) affects reproductive biology in Pyrostegia venusta (Bignoniaceae) growing at Agra and Mysore. At Agra, the species flowers profusely during December to March, but fails to bear fruits. At Mysore, on the other hand it flowers during November to February and produces well developed fruits with winged seeds.