Circadian regulation of breath alcohol concentration.

Study Objectives: The role of the circadian clock in regulating blood/breath alcohol levels after consuming alcohol is uncertain. Our goal was to evaluate the degree to which the circadian system regulates breath alcohol concentration (BrAC) pharmacokinetic parameters.

Methods: Twenty healthy adults aged 21-30 years took part in a 4-day laboratory study.

Differential effects of split and continuous sleep on neurobehavioral function and glucose tolerance in sleep-restricted adolescents.

Study Objectives: Many adolescents are exposed to sleep restriction on school nights. We assessed how different apportionment of restricted sleep (continuous vs. split sleep) influences neurobehavioral function and glucose levels.

A single night of sleep loss impairs objective but not subjective working memory performance in a sex-dependent manner.

Acute sleep deprivation can lead to judgement errors and thereby increases the risk of accidents, possibly due to an impaired working memory. However, whether the adverse effects of acute sleep loss on working memory are modulated by auditory distraction in women and men are not known. Additionally, it is unknown whether sleep loss alters the way in which men and women perceive their working memory performance.

Learning performance is linked to procedural memory consolidation across both sleep and wakefulness.

We investigated whether learning performance in a procedural finger tapping task before nocturnal sleep would predict performance gains after sleep in 60 young adults. Gains were defined as change in correctly tapped digit sequences between learning (12 trials administered in the evening) and retesting (3 trials administered in the morning after sleep). The same task was also administered to a separate wake group (N = 54 young adults), which learned in the morning and was retested in the evening.