Modulated-Diameter Zirconia Nanotubes for Controlled Drug Release-Bye to the Burst.

The performance of an orthopedic procedure depends on several tandem functionalities. Such characteristics include materials' surface properties and subsequent responses. Implant surfaces are typically roughened; this roughness can further be optimized to a specific morphology such as nanotubular roughness (ZrNTs) and the surfaces can further be used as static drug reservoirs.

Wetting behavior of zirconia nanotubes.

In this work, we investigate the wettability of ZrO nanotubes (ZrNT) synthesized electrochemical anodization of zirconium. The ZrNT surface shows super-hydrophilic behavior while the octadecylphosphonic acid (CHPO(OH)) modified surface shows super-hydrophobic behavior. We demonstrate that the wetting properties are independent of ZrO nanotube geometry and length.