Thiadiazole Functionalized Salicylaldehyde-Schiff Base as a pH-responsive and chemo-reversible "Turn-Off" fluorescent probe for selective cu (II) detection: Logic Gate Behaviour and Molecular Docking Studies.

A novel thiadiazole functionalized schiff base chemoreceptor (E)-2,4-dichloro-6-(((5-mercapto-1,3,4-thiadiazol-2-yl)imino)methyl)phenol (SB-1) has been synthesized and characterized spectroscopically by using various techniques. Its photophysical behaviour was scanned towards a variety of metal ions in mixed aqueous media. The chemosensor (SB-1) displayed excellent selectivity towards Cu ion through fluorescent diminishment (turn-off phenomenon).

Self-assembly of β-alanine homotetramer: formation of nanovesicles for drug delivery.

The present paper describes the fabrication of nanovesicles using the stirring induced self-assembly of a β-alanine homotetramer (HN-βAla-βAla-βAla-βAla-CONH) in an aqueous medium. Dynamic light scattering (DLS) studies revealed the formation of nanostructures with an average particle size of ∼463 nm. The morphology and size of the nanostructures was also confirmed by electron microscopy.