Effect of preparation method and storage period on the stability of saliva DNA.

Unlabelled: Saliva is an attractive source for oral microbial detection and quantification since sampling is non-invasive and rapid.

Objectives: To determine whether different saliva preparation methods or preservation time periods affect DNA stability.

Methods: Saliva samples from 4 healthy adult volunteers were processed to obtain 3 different preparations: whole saliva, and after centrifugation pellet and supernatant.

Commencement of warfarin therapy in children following the Fontan procedure.

Introduction: Following the Fontan procedure, children require lifelong anticoagulant therapy to minimise the risk of thrombosis. Factors influencing the management of warfarin therapy in children post-Fontan procedure are poorly understood. This study investigated factors affecting warfarin therapy stability and time to reach target therapeutic range, in children post-Fontan procedure.