Neuropathic Pain in Guillain-Barre Syndrome: Association with Rehabilitation Outcomes and Quality of Life.

Background: Neuropathic pain contributes significantly to the morbidity and affects the quality of life adversely in Guillain-Barre syndrome (GBS).

Objective: To study neuropathic pain profile in GBS and association with rehabilitation outcomes and effect on the quality of life.

Methods: Observational study conducted in rehabilitation setting of a tertiary care hospital among adult GBS patients of less than 3 months duration.

Glucocorticoid-Induced Osteoporosis Prevention in Polymyalgia Rheumatica Patients.

Aim Studies indicate that <50% of polymyalgia rheumatica (PMR) patients receive bone protective therapy (BPT) forglucocorticoid-induced osteoporosis (GIOP) prevention. We sought to determine if PMR patients are protected fromGIOP by examining bone densitometry (DXA) scan results, BPT use, and adherence to guidelines. Methods PMR patients treated with glucocorticoids who underwent a DXA scan at Cork University Hospital from 01/01/2016 to27/10/2017 were included.

Cutaneous leishmaniasis in Bikaner, India: Clinicoepidemiological profile; parasite identification using conventional, molecular methods and CL Detect™ rapid test, a new Food and Drug Administration-approved test.

Background And Objective: Cutaneous Leishmaniasis (CL) is a dermal manifestation caused by various species of Leishmania. This is the most common Leishmanial syndrome seen worldwide and is emerging as and threatens to become an uncontrollable disease. The present study was planned to understand the current epidemiology of CL in the conventionally endemic area of Bikaner, Rajasthan.

Updates on the biology of serotonin and tryptophan hydroxylase.

Purpose Of Review: To summarize the most recent findings relevant to the biology of serotonin (5-hydroxytryptamine; 5-HT) and the enzyme tryptophan hydroxylase (TPH) in human gastrointestinal disease.

Recent Findings: Serotonin is synthesized in the central nervous system (CNS) and the gastrointestinal tract where it is secreted from enteroendocrine cells. Its biosynthesis is regulated by two isoforms of the enzyme TPH of which TPH1 is localized predominantly in gastrointestinal enteroendocrine cells.

Pulmonary cryptosporidiosis in an immunocompetent host treated successfully with nitazoxanide.

Cryptosporidium parvum is an intracellular spore-forming protozoa which predominantly causes intestinal diseases. It causes severe and life-threatening diarrheal diseases in immunocompromised hosts and usually self-limiting disease in immunocompetent hosts. Extra-intestinal manifestations of cryptosporidium infection are very rare.

Chronic invasive fungal rhinosinusitis by Paecilomyces variotii: A rare case report.

Fungal infection of the paranasal sinuses is an increasingly recognised entity, both in normal and immunocompromised individuals. The recent increase in mycotic nasal and paranasal infections is due to both improved diagnostic research and an increase in the conditions that favour fungal infection. Aspergillus, Candida, and Mucor species are the most common causative agents of fungal sinusitis, but infection with lesser known species have been reported across the world infrequently.

A new tool for sharing and querying of clinical documents modeled using HL7 Version 3 standard.

We present a new software tool called CDN (Collaborative Data Network) for sharing and querying of clinical documents modeled using HL7 v3 standard (e.g., Clinical Document Architecture (CDA), Continuity of Care Document (CCD)).