Significance of oxidative stress in liver damage of male and female rats with simulated ethanol hepatitis.

Objective: Aim: to find out the gender characteristics of oxidative mechanisms of liver damage in rats with ethanol hepatitis (EH).

Patients And Methods: Materials and Methods: The study was performed on 48 white male and female rats: 1 - control, 2 - acute EH (12,5 ml/kg of a 40% ethanol solution prepared on 5% solution of glucose for 7 days).The diene and triene conjugates (DC, TC), Schiff's bases (SB), TBA-active products (TBA-ap), activity of superoxide dismutase (SOD) and catalase (CAT) were determined in the blood serum.

The association of angiotensin-converting enzyme gene insertion/deletion polymorphism with bronchial asthma.

Bronchial asthma (BA) is among the most prevalent chronic inflammatory disorders of the lung airways, and it has become clear that a mixture of genetic predisposition and environmental factors plays a critical role in its pathogenesis. The aim of presented review is to analyze the published data on the possible role of ACE gene polymorphism in BA development. The article is based on available literature found in Pubmed, Elsevier, Scopus, and Google scholar databases.

Observation of serious adverse cardiovascular events over 3 years in patients with advanced atherosclerosis: is there a gender difference?

Unlabelled: Dyslipidemia has been widely acknowledged as one of the major predisposing factors for the development and progression of atherosclerosis. While advanced atherosclerosis confirmed to influence the prognosis of patients with acute coronary syndrome (ACS), it has not yet been established, whether this impact is gender-dependent.

Aim: The aim of study was to investigate possible gender-related effect of dyslipidemia and generalized atherosclerosis on the long-term outcomes in patients with ACS.