The spectrum of SDHD mutations in Russian patients with head and neck paraganglioma.

Aim Of The Study: It was found that the mutations in the SDHD gene, encoding one of subunits of the succinate dehydrogenase complex, lead to the development of head and neck paraganglioma (HNPGL). We analyzed this gene in 91 patients with HNPGL from Russia.

Materials And Methods: DNA was isolated from the whole blood.