Publications by authors named "Svetlana Pesegova"
Article Synopsis
- Radiotherapy can lead to premature ovarian failure and infertility in cancer patients, highlighting the need for ovarian radioprotection methods.
- Electron irradiation is a promising but under-researched option that has less toxic effects on surrounding tissues compared to other radiation types.
- The study shows that leukocyte-poor platelet-rich plasma can mitigate the negative effects of electron irradiation on ovarian function by promoting healing and reducing inflammation through specific cellular mechanisms.
A better understanding of the pathogenesis of preterm birth (PTB) will allow us to lower the PTB rate, reducing perinatal morbidity and mortality. This article presents the hypothesis that premature placenta apoptosis could be a potential cause of PTB. We evaluated gene expression involved in apoptosis: caspase-3, caspase-8, and XIAP (X-linked inhibitor of apoptosis) in the placenta during pregnancy (n = 41), at the onset of preterm labour (n = 42), after preterm (n = 44) and term (n = 32) labour.
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