[Deep sedation with midazolam and propofol in children undergoing ambulatory magnetic resonance imaging of the brain].

Unlabelled: BACKROUND/AIM: Sedation is necessary in children undergoing magnetic resonance imaging (MRI) to ensure motionless. The success of sedation is typically measured by two factors: safety (lack of adverse events) and effectiveness of the procedure (successful completion of the diagnostic examination). Propofol is frequently used to induce deep sedation in children.

[New therapy strategies for treatment of severe sepsis and septic shock in intensive care unit of clinical centre in Kragujevac].

Introduction: Despite numerous advances in medicine, the mortality rate of severe sepsis and septic shock remains high, 30-50%. New therapy strategies include: early goal-directed therapy, fluid replacement, early and appropriate antimicrobials, source of infection control, use of corticosteroids, vasopressors and inotropic therapy, use of recombinant activated protein C, tight glucose control, low-tidal-volume mechanical ventilation. They have been shown to improve the outcomes.