Publications by authors named "Svetlana Bondar"
Article Synopsis
- The study focuses on the role of mobile genetic elements in spreading biocide and antibiotic resistance among bacteria, specifically the qacEΔ1 gene that provides resistance to quaternary ammonium compounds (QACs).
- Researchers developed a TaqMan real-time PCR assay to detect the qacEΔ1 gene in Gram-negative bacteria, which can accurately identify even low quantities (as few as 80 copies) without false results.
- This assay serves as a rapid, sensitive, and specific method for monitoring QAC resistance, tracking the spread of class 1 integrons, and predicting multidrug-resistant (MDR) traits in Gram-negative bacteria.
Objectives: Antibiotic overuse is a significant problem in nursing homes (NHs). Strategies to improve antibiotic prescribing practices in NHs are a critical need. In this study, we analyzed antibiotic prescribing workflows to identify strategies for improving antibiotic prescribing in NHs.
View Article and Find Full Text PDFHeart failure patients are routinely given beta-adrenoceptor antagonists (beta-blockers), although the mechanism(s) underlying their beneficial effects is not fully resolved. It is not entirely clear how long-term application of negative inotropic compounds improves cardiac performance, slows remodeling processes, and decreases mortality. All beta-blockers, which produce a beneficial effect in heart failure, have in common a high degree of lipophilicity and, therefore, have the ability to cross the blood-brain barrier.
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