Genotoxic and Anti-Genotoxic Potential of Hydrosols from Water-Steam Distillation of Oil-Bearing Roses L. and L. from Bulgaria.

L. and L. (Rosaceae) are grown as raw materials for valuable essential oils and hydrosols.

Cytogenetic Studies on Genoprotective Effect of Mill. Hydrosol in Plant and Lymphocyte Test Systems.

Bulgarian Mill. is has been known since ancient times for its high-quality oil, hydrosol, and other aromatic products. Rose hydrosol has various biological activities, but no research on its anticytotoxic/antigenotoxic effects exists.

Study on Cytotoxic and Genotoxic Potential of Bulgarian Mill. and L. Hydrosols- and .

The L. and Mill. growing in Bulgaria are known for their extremely fine essential oil and valuable hydrosols.

The Anti-Genotoxic Activity of Wastewaters Produced after Water-Steam Distillation of Bulgarian Mill. and L. Essential Oils.

The steam distillation of valuable rose essential oil from Mill. and L. generates large volumes of wastewaters.

Rose Flowers-A Delicate Perfume or a Natural Healer?

Plants from the Rosacea family are rich in natural molecules with beneficial biological properties, and they are widely appreciated and used in the food industry, perfumery, and cosmetics. In this review, we are considering Mill., L.

How can the natural radiation background affect DNA integrity in angiosperm plant species at different altitudes in Rila Mountain (Southwest Bulgaria)?

Climate changes and anthropogenic factors are the main factors contributing to the destruction of natural ecosystems. The aim of this study was to investigate the extent to which wild plants adapt to UV, gamma background, and gross beta activity, as well as the possible damage that can be recorded in plants growing at different altitudes in Rila Mountain. We used physicochemical, cytogenetic, and molecular methods.

Lilium compounds kaempferol and jatropham can modulate cytotoxic and genotoxic effects of radiomimetic zeocin in plants and human lymphocytes In vitro.

Organisms are constantly exposed to the detrimental effect of environmental DNA-damaging agents. The harmful effects of environmental genotoxins could be decreased in a viable way by antimutagenesis. One of the modern approaches to reduce the mutagenic burden is based on exogenous natural and synthetic compounds that possess protective and antimutagenic potential against genotoxins.

Cytotoxic and clastogenic activity of CdCl2 in human lymphocytes from different donors.

The sensitivity of human lymphocytes from different donors to CdCl2 using a complex of methods for determination of cytotoxicity and genotoxicity was studied. As endpoints for cytotoxicity the mitotic index (MI) and apoptosis were evaluated. To indicate genotoxicity chromosome aberrations test (CA) was used.

The potential of synthetic thiourea compound to reduce the cytotoxic and genotoxic effects of paraquat in Hordeum vulgare and cultured human lymphocytes.

This work evaluated the ability of one synthetic compound 1-(4-fluorophenylthiocarbamoyl)-4-methyl-piperazine (FTMP), thiourea derivative to reduce cytotoxic and genotoxic effects of free radical inducer paraquat (PQ) in two different test systems Hordeum vulgare and human lymphocytes in vitro. The mitotic index was used as a marker for cytotoxicity. To indicate genotoxicity, chromosome aberrations test and micronucleus induction test were used.

Cytotoxic and genotoxic effects of paraquat in Hordeum vulgare and human lymphocytes in vitro.

Two phylogenetically distant types of test-systems-root tip meristems of barley (Hordeum vulgare) and human lymphocytes in vitro were used to detect genotoxicity and cytotoxicity induced by the herbicide paraquat (PQ) in the concentration range (10(-6) to 5 x 10(-4) mol/l). As an endpoint for cytotoxicity the mitotic index (MI) was evaluated. The frequency of chromosome aberrations (CA) and the frequency of micronuclei (MN) were used as endpoints for genotoxicity.