Publications by authors named "Svenja-K Otto"

Lithium-metal batteries with a solid electrolyte separator are promising for advanced battery applications, however, most electrolytes show parasitic side reactions at the low potential of lithium metal. Therefore, it is essential to understand how much (and how fast) charge is consumed in these parasitic reactions. In this study, a new electrochemical method is presented for the characterization of electrolyte side reactions occurring on active metal electrode surfaces.

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Article Synopsis
  • Understanding contamination and surface treatment of lithium metal anodes is crucial for improving all-solid-state batteries.
  • Time-of-flight secondary ion mass spectrometry (ToF-SIMS) is a surface-sensitive method that analyzes LMA surfaces but can be complex to interpret manually.
  • This study utilizes machine learning, specifically logistic regression, to effectively identify lithium compounds from ToF-SIMS data, enhancing analysis and accuracy for both known and new samples.
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Within this study, the authors use human mesenchymal stem cells incubated with silver nanoparticles (AgNPs) as a model system to systematically investigate the advantages and drawbacks of the fast imaging delayed extraction mode for two-dimensional and three-dimensional (3D) analyses at the cellular level. The authors compare the delayed extraction mode with commonly employed measurement modes in terms of mass and lateral resolution, intensity, and dose density. Using the delayed extraction mode for single cell analysis, a high mass resolution up to 4000 at m/z = 184.

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Drug functionalization of biomaterials is a modern and popular approach in biomaterials research. Amongst others this concept is used for the functionalization of bone implants to locally stimulate the bone healing process. For example strontium ions (Sr) are administered in osteoporosis therapy to stimulate bone growth and have recently been integrated into bone cements.

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