Publications by authors named "Svenja Kristin Tetzlaff"
Article Synopsis
- Intravital 2P-microscopy facilitates the study of brain tumor behavior in mouse cortex, previously limited by imaging challenges in deep brain areas.
- The new Deep3P imaging workflow combines microscopy with artificial intelligence, allowing researchers to visualize glioblastoma infiltrating up to 1.2 mm into the brain.
- The study reveals that glioblastoma primarily invades through blood vessels in the white matter, and identifies potential imaging biomarkers associated with early tumor colonization.
Glioblastomas are incurable tumors infiltrating the brain. A subpopulation of glioblastoma cells forms a functional and therapy-resistant tumor cell network interconnected by tumor microtubes (TMs). Other subpopulations appear unconnected, and their biological role remains unclear.
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