Acrometastasis as the first sign of an occult non-small cell carcinoma of lung.

This case study reports a rare case of acrometastasis to the right middle finger middle phalanx as the first sign of an occult non-small cell carcinoma of the lung.

[Prevention of skeletal related events in patients with bone metastases from solid tumours].

This article is based on a systematic literature search and meta-analyses of clinical data regarding effects of bisphosphonates (BP) and denosumab (DS) on preventing skeletal related events (SRE) in patients with bone metastases from solid tumours. Although there are pharmacological differences between the different types of BP no major differences were observed between BP in preventing SRE or in adverse events. Treatment with DS has in three randomised trials showed a greater effect than BP in preventing SRE.

[The dying patient].

It is important for dying patients that their doctors are trained to diagnose that death is near. Typical clinical signs of impending death are described: the patient is bedbound, semicomatose, only able to take sips of fluid and no longer able to take oral drugs. Care of the dying is exclusively focused on palliation.