Pulmonary function, working capacity and strength in young adults with Marfan syndrome.

Objective: To investigate pulmonary function, working capacity and isokinetic muscle strength in subjects with Marfan syndrome.

Materials And Methods: Seventeen subjects, mean age 23 years, performed spirometry, maximal ergometer cycle tests and knee extension and flexion isokinetic torque tests.

Results: The subjects with Marfan syndrome had increased total and residual lung volume values compared with predicted values in healthy subjects and reduced peak oxygen uptake compared with healthy subjects of the same age.