Pain mechanistic networks: the development using supervised multivariate data analysis and implications for chronic pain.

Chronic postoperative pain is present in approximately 20% of patients undergoing total knee arthroplasty. Studies indicate that pain mechanisms are associated with development and maintenance of chronic postoperative pain. The current study assessed pain sensitivity, inflammation, microRNAs, and psychological factors and combined these in a network to describe chronic postoperative pain.

Motion verb sentences activate left posterior middle temporal cortex despite static context.

The left posterior middle temporal region, anterior to V5/MT, has been shown to be responsive both to images with implied motion, to simulated motion, and to motion verbs. In this study, we investigated whether sentence context alters the response of the left posterior middle temporal region. 'Fictive motion' sentences are sentences in which an inanimate subject noun, semantically incapable of self movement, is coupled with a motion verb, yielding an apparent semantic contradiction (e.

Concrete spatial language: see what I mean?

Conveying complex mental scenarios is at the heart of human language. Advances in cognitive linguistics suggest this is mediated by an ability to activate cognitive systems involved in non-linguistic processing of spatial information. In this fMRI-study, we compare sentences with a concrete spatial meaning to sentences with an abstract meaning.