Publications by authors named "Sven Straumann"
Objective: Clinical visual intraoperative electrocorticography (ioECoG) reading intends to localize epileptic tissue and improve epilepsy surgery outcome. We aimed to understand whether machine learning (ML) could complement ioECoG reading, how subgroups affected performance, and which ioECoG features were most important.
Methods: We included 91 ioECoG-guided epilepsy surgery patients with Engel 1A outcome.
Article Synopsis
- The Kaplan-Meier method can overestimate the risk of cancer coming back, especially when other events like death happen first, but the Aalen-Johansen method can give a more accurate picture by considering these events.
- A study looked at research articles about meningiomas (a type of brain tumor) since 2020 and found that only a few used the better method.
- It showed that not using the Aalen-Johansen method mostly led to overestimating the recurrence risk, especially in older patients with more serious tumors.
Objective: The modern management of patients with Koos grade IV vestibular schwannomas (VSs) aims at functional preservation and long-term tumor control. Gross-total resection (GTR) leads to optimal tumor control but frequently also results in permanent facial nerve (FN) palsy. Subtotal resection (STR) or near-total resection (NTR) followed by a wait-and-scan protocol and second-line radiation therapy (RT) in case of progressive residuals yields excellent tumor control rates with less permanent morbidity.
View Article and Find Full Text PDFPurpose Of Review: In order to better treat pain, we must understand its architecture and pathways. Many modulatory approaches of pain management strategies are only poorly understood. This review aims to provide a theoretical framework of pain perception and modulation in order to assist in clinical understanding and research of analgesia and anesthesia.
View Article and Find Full Text PDFMRI and intraoperative electrocorticography are often used in tandem to delineate epileptogenic tissue in resective surgery for focal epilepsy. Both the resection of the MRI lesion and tissue with high rates of electrographic discharges on electrocorticography, e.g.
View Article and Find Full Text PDFIntraoperative electrocorticography using high-frequency oscillations or spikes to tailor epilepsy surgery in the Netherlands (the HFO trial): a randomised, single-blind, adaptive non-inferiority trial.
Lancet Neurol
November 2022
Article Synopsis
- In this study, researchers wanted to find out if a new way of guiding epilepsy surgery using high-frequency oscillations (HFOs) was just as good as the traditional way using spikes to help stop seizures.
- They looked at both children and adults and assigned them randomly into two groups, one for HFO-guided and the other for spike-guided surgery, to see who had fewer seizures after one year.
- After one year, they found that 67% of the people in the HFO group had no seizures, which means this method could be a promising alternative to the old way!
Context: Hypogonadism is highly prevalent among obese men with metabolic syndrome. Chronic low-grade inflammation is suspected to be a major cause for low testosterone levels in obese individuals.
Objectives: To test the inflammatory hypothesis of testosterone deficiency in metabolic syndrome.