Publications by authors named "Sven L Gallo"
Article Synopsis
- - This study focuses on identifying potential failure modes in the administration of radiopharmaceutical therapies (RPTs) like DOTATATE (LUTATHERA) and PSMA-617 (PLUVICTO) through failure mode and effects analysis (FMEA) and fault tree analysis (FTA) methods, emphasizing the need for collaboration between nuclear medicine and radiation oncology departments.
- - A literature review and FMEA survey conducted across multiple centers revealed critical failure areas such as non-optimized treatment delivery, inadequate patient monitoring, and insufficient safety training, leading to risks of radiation contamination.
- - The study concludes by highlighting the importance of improving quality management practices in RPTs to enhance treatment safety, while also advocating for more prospective risk analysis
The lesion detection performance of SPECT and PET scanners is most commonly evaluated with a phantom containing hollow spheres in a background chamber at a specified radionuclide contrast ratio. However, there are limitations associated with a miniature version of a hollow sphere phantom for small-animal SPECT and PET scanners. One issue is that the 'wall effect' associated with zero activity in the sphere wall and fill port causes significant errors for small diameter spheres.
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