[Oral manifestations in HIV infection].

In this review article, oral lesions in relation to HIV infection are presented and discussed. Lesions such as oral candidiasis, hairy leukoplakia and necrotising gingivitis or periodontitis may be the first sign of an HIV infection or of its progression. Almost all HIV-infected patients will contract oral diseases.

[A 35-year-old man with aggressive periodontitis].

Background: Aggressive and necrotic periodontal diseases may occasionally be associated with undiagnosed systemic diseases and immune deficiencies. We present a 35-year-old man with an undiagnosed hypo-gammaglobulinaemia and severe aggressive periodontitis.

Material And Methods: Gingival biopsies and peripheral blood were collected for immunohistochemical and cell culture studies from the patient with aggressive periodontitis, 3 patients with chronic periodontitis and 3 controls.

[A patient with periodontitis, oral candidiasis and undiagnosed HIV infection].

Background: HIV infection may be associated with necrotic periodontal disease, oral candidiasis and idiopathic thrombocytopenic purpura.

Material, Methods And Results: A 38-year-old man with necrotic periodontal disease and oral candidiasis was referred to the Department of Periodontology, University of Oslo. With a diagnosis of idiopathic thrombocytopenic purpura he received immunosuppressive medication and had been splenectomized without any improvement.

Highly increased numbers of leukocytes in inflamed gingiva from patients with HIV infection.

Background: HIV infection increases susceptibility for marginal periodontitis, with horizontal and rapid loss of periodontal soft tissues and alveolar bone.

Objectives: To examine whether numbers, distribution and some properties of mast cells, neutrophils and macrophages are normal in chronically inflamed gingiva of HIV-positive patients.

Methods: Gingival biopsies were stained for mast cell tryptase and chymase, neutrophil elastase, CD68, human transforming growth factor beta(1), HLA-DR, Fc gamma RI, Fc gamma RII and Fc gamma RIII and calprotectin.