Non-coding RNAs and neuroinflammation: implications for neurological disorders.

Neuroinflammation is considered a balanced inflammatory response important in the intrinsic repair process after injury or infection. Under chronic states of disease, injury, or infection, persistent neuroinflammation results in a heightened presence of cytokines, chemokines, and reactive oxygen species that result in tissue damage. In the CNS, the surrounding microglia normally contain macrophages and other innate immune cells that perform active immune surveillance.

Symptoms of depression and internalizing problems in early adulthood - associated factors from birth to adolescence.

Purpose: Even though the mechanisms behind the development of depression and internalizing problems remains unknown, many different factors have been shown to increase the risk. Longitudinal studies enable the investigation of exposure during different developmental periods during childhood. This study aims to examine factors associated with depressive and internalizing problems at age 20 in terms of sociodemographic factors, previous mental health problems and stressful life events during childhood, adolescence, and early adulthood.

Predictors of educational failure at 16 and 19 years of age-SESBiC longitudinal study.

Background: Educational attainment is highly associated with future health and independence. Throughout childhood, children are exposed to factors that may promote educational attainment and factors that may be associated with a reduced likelihood of being able to complete their education. The purpose of the current study was to investigate which factors, measured from birth up to finishing upper secondary school, were associated with a lower mean grade point average from lower and upper secondary school as well as eligibility to upper secondary school and college/university.

Patterns of disclosure and perceived societal responses after child sexual abuse.

Background: Disclosure of child sexual abuse (CSA) is key for abused children to access help and to protect them and other children.

Objective: The aim of this study was to investigate patterns of disclosure of child sexual abuse and how children perceived responses from people they disclosed to.

Participants And Setting: Data were collected online in classrooms and during home studies in a national probability-based sample of 3282 third-year students in Swedish high schools in 2020-2021 (the age of the students varied between 16 and 23 years (M = 18,2)).

Resilience in Swedish adolescents-Does resilience moderate the relationship between trauma experience and trauma symptoms?

Background: Research shows child abuse to be devastating for psychological health, but children and adolescents display varying reactions from maltreatment. Resilience is known as a protective factor, but sparse research is conducted on adolescents or assess resilience with consideration of ecological theories. Adolescent Resilience Questionnaire (ARQ) was developed to assess the five dimensions: Individual, Family, Peers, School, and Community and covers the broader ecological resilience spectrum.

Psychometric properties of the Adolescent Resilience Questionnaire (ARQ) in a sample of Swedish adolescents.

Background: The importance of resilience, and interest in it, has increased markedly in recent years, based on the need to understand why some children and young people have a resilience to stress that others lack. At the same time, there has been a lack of instruments to measure resilience. The aim of this study was to translate the Adolescent Resilience Questionnaire (ARQ) into Swedish and investigate the psychometrics of this Swedish version.

Vulnerability and stressors on the pathway to depression in a global cohort of young athletics (track and field) athletes.

This research set out to identify pathways from vulnerability and stressors to depression in a global population of young athletes. Retrospective data were collected at age 18-19 years from Athletics athletes (n = 1322) originating from Africa, Asia, Europe, Oceania, and the Americas. We hypothesised that sports-related and non-sports-related stressors in interaction with structural vulnerability instigate depression.

Lifetime Prevalence of Verbal, Physical, and Sexual Abuses in Young Elite Athletics Athletes.

To examine prevalence of verbal, physical, and sexual abuses in young elite athletes, a cross sectional questionnaire-based survey was conducted during the World Athletics under 20 World Championships. This questionnaire aimed at distinguishing between abuses perpetrated in the context of Athletics from those which were unrelated to Athletics. Four hundred and eighty athletes (52.

Maternal temperament and character: associations to child behavior at the age of 3 years.

Background: The influence of maternal temperament on child behavior, and whether maternal temperament impact boys and girls differently is not thoroughly studied. The aim was to investigate the impact of maternal temperament and character on child externalizing and internalizing problems at age 3.

Methods: A birth-cohort of 1723 mothers and their children were followed from birth to age 3.

Delayed healthcare access among victims of sexual abuse, understood through internal and external gatekeeping mechanisms.

Background: Sexual abuse is associated with severe health consequences, and the European Union has, through the Istanbul Convention, urged its member countries to provide specialist care for victims of sexual abuse.

Aim: This aim of this study was to investigate patient- and abuse-related characteristics among patients seeking help at a specialist clinic in Sweden, with focus on disclosure, mental health and appropriate healthcare access.

Methods: This is a descriptive study where journal data from 100 consecutive patients January 2017 to February 2018 were analyzed.

Psychometric properties of the Child and Adolescent Trauma Screen (CATS) in a sample of Swedish children.

Objective: The aim of this study was to investigate the psychometrics of the Swedish version of the Child and Adolescent Trauma Screen (CATS). This was to obtain access to an international instrument to identify symptoms of post-traumatic stress in children and adolescents according to the new Diagnostic and Statistical Manual for Mental Disorders, 5th edition (DSM-5).

Method: A total of 591 young Swedish schoolchildren aged 13-17 years old were given the CATS together with the Trauma Symptom Checklist for Children (TSCC), and the Linköping Youth Life Experience Scale (LYLES-Y).

A One-Session Treatment of PTSD After Single Sexual Assault Trauma. A Pilot Study of the WONSA MLI Project: A Randomized Controlled Trial.

Sexual abuse is a crime with devastating health consequences. Accessible, acceptable and affordable treatment of PTSD after sexual abuse is important. In this pilot study, a one-session PTSD treatment and a modified perspective to PTSD treatment is introduced.

Improved Intelligence, Literacy and Mathematic Skills Following School-Based Intervention for Children in Foster Care.

Interventions aimed at improving school performance for children in foster care are few and are generally not implemented. By preventing failure in school, the prospect of reducing the risk for future poor health, substance abuse, unemployment, and other detrimental social conditions are met. This paper focuses on the change of preconditions for compulsory school performance in out-of-home care children, following an intervention called "Skolfam" that aims to improve school performance by individual assessments and school-based interventions.

Child physical abuse, declining trend in prevalence over 10 years in Sweden.

Aim: To study trends in prevalence and risk factors of child physical abuse over 10 years in Sweden.

Methods: This study analysed responses from school surveys in 2008, 2011, 2014 and 2017 in Södermanland County, Sweden with average 5125 respondents per year, 15 and 17 years old. There were identical questions on exposure to violence and risk factors including parental employment, separated parents, disability or disease, foreign background and lack of adult support.

Health care consumption among adolescent girls prior to diagnoses of sexual abuse, a case-control study in the Stockholm Region.

Victims of sexual abuse have more co-morbidities than other persons in the same age and the most affected group are adolescent girls. Little is known about how this is reflected in health care consumption patterns prior to the registered diagnosis. The aim of this investigation was to study health care consumption patterns among girls, 12-17 years old, 1 and 2 years prior to their diagnoses of sexual abuse.

Online sexual abuse of adolescents by a perpetrator met online: a cross-sectional study.

Background: The current study aimed at exploring adolescents' experiences of online sexual contacts leading to online sexual abuse by a perpetrator whom the victim had first met online. Associations with socio demographic background, experience of abuse, relation to parents, health and risk behaviors were studied.

Methods: The participants were a representative national sample of 5175 students in the third year of the Swedish high school Swedish (M age = 17.