ELECTROMAGNETIC STIMULATION REGULATES BLOOD CORTICOSTERONE LEVELS IN IMMOBILIZED RATS: GENDER DIFFERENCES.

A mental disorder is a condition that affects an individual's cognition, emotional regulation, or behavior, causing distress or impairing main areas of functioning. The effects of electromagnetic stimulation (EMS) and oxytocin (OXY) on blood corticosterone (CORT) levels in immobilized (10 days, 2 hours a day or one time, 2 hours) male and female rats while accounting for their sex hormone levels were studied. The experiments were conducted on intact and gonadectomized rats.

ELECTRIC-MAGNETIC STIMULATION PREVENTS STRESS-INDUCED DETERIORATION OF SPATIAL MEMORY.

In response to physical and psychological stressors, neurobiological processes are activated to maintain homeostasis. Stress alters the activity of the hypothalamic-pituitary-adrenal (HPA) axis. The mechanism for this effect is not yet clear.

GENDER RELATED DIFFERENCES IN SEX HORMONE-MEDIATED ANXIOLYTIC EFFECTS OF ELECTROMAGNETIC STIMULATION DURING IMMOBILIZATION STRESS.

Physical and psychological stressors activate the hypothalamic-pituitary-adrenal axis (HPA). Elevated glucocorticoid levels over a long time harm neurocognitive and neurobiological development and cause deleterious effects. The effects of glucocorticoids depend not only on the concentration and duration of action, but also on the period of life when the effect occurs and gender.

NORMALIZING EFFECT OF ELECTROMAGNETIC STIMULATION ON BLOOD QUANTITATIVE INDICES IN DEPRESSED RATS ON THE BACKGROUND OF OXYTOCIN.

Depression is linked to systemic inflammation. There is an association between blood cell count and/or hematological inflammatory markers with depression symptoms. Oxytocin reduces the activity of brain regions that produce anxiety and might involve in the rehabilitation of depressive-like behavior.

POSSIBLE EFFECTS OF ELECTRIC-MAGNETIC STIMULATION ON HYPOTHALMIC-HYPOPHISIAL-ADRENAL AXIS: BEHAVIOURAL STUDY.

The goal of this investigation was to study the effect of the electric-magnetic stimulation (EMS) on the activity of the HPA axis, which can change behavior activity. The experiments were conducted on mongrel, albino male rats, weighing 150- 200 g (n=14). Proceeding from the goals set, the experimental group (dexamethasone-treated-1mg/ per animal for 10 days) and the control group of rats were involved in the experiments.

THE ACOUSTIC RANGE ELECTRIC-MAGNETIC FIELD EFFECT ON THE PASSIVE AVOIDANCE TASK IN DEPRESSED RATS.

Depression linked to memory problems, such as forgetfulness or confusion. Stress and anxiety can also lead to poor memory. Memory processes are affected by repeated electric-magnetic stimulation (EMS).

POSSIBLE IMPLEMENTATION OF GABAERGIC AND GLUTAMATERGIC SYSTEMS IN REALIZATION OF ANTIEPILEPTIC EFFECTS OF ACOUSTIC RANGE ELECTRO - MAGNETIC FIELDS.

Seizure is a clinical manifestation of a hyperexcitable neuronal network, in which, the electrical balance underlying the normal neuronal activity is altered pathologically-excitation (Glutamatergic activity) predominates over inhibition (GABAergic activity). Arresting of seizure activity is carried out by restoration of neurotransmitter balance. This process has a direct relation with ion channel permeability in cell and ion transmembrane movement.

Evaluation of multiple measures of antiretroviral adherence in the Eastern European country of Georgia.

Introduction: There is little information on adherence to antiretroviral therapy (ART) in the Eastern European region. This prospective study evaluated multiple measures of adherence and their association with viral suppression among HIV patients in Georgia.

Methods: A prospective cohort study enrolled 100 consecutive antiretroviral-naïve adult (age ≥ 18 years) patients, who were followed for three months.

Fibroscan and FibroTest/FibroMax to assess liver fibrosis/cirrhosis in patients with chronic HBV and HCV infection in Georgia.

Although, liver biopsy is the gold standard in assessment of the degree of liver damage, the method has some limitations. For this reason, assessment of liver damage using non-invasive methods is currently an important topic in hepatology. The aim of the study was to evaluate liver fibrosis/cirrhosis using Transient Elastography and FibroTest/FibroMax in patients with chronic HCV and HBV infection in Georgia and to compare Fibroscan and FibroTest/FibroMax results.

[Side effects of the combined antiviral therapy in patients with chronic hepatitis C].

The aim of the study is to reveal and treat the side effects of the combined antiviral therapy - Peginterferon and Ribavirin in patients with chronic Hepatitis C. During 2004-2006 years, 40 patients in the ambulatory department of the Infectious Diseases Clinic of the State Medical University were investigated. All the patients were administered pegilated interferon and ribavirin after special procedures.

[An unusual course of viral hepatitis A in children].

To determine the present-day specific clinical features of viral hepatitis A (HA) in children, observation on 447 children aged 1 year and 10 months to 14 years with verified HA monoinfection was carried out. At the season of 1993 essential differences were observed in the clinical picture of HA: the disease took a more severe course with the prevalence of medium-severe (59.3%) and severe (3.