Mucosal metabolites fuel the growth and virulence of E. coli linked to Crohn's disease.

Elucidating how resident enteric bacteria interact with their hosts to promote health or inflammation is of central importance to diarrheal and inflammatory bowel diseases across species. Here, we integrated the microbial and chemical microenvironment of a patient's ileal mucosa with their clinical phenotype and genotype to identify factors favoring the growth and virulence of adherent and invasive E. coli (AIEC) linked to Crohn's disease.

Structure and Distribution of Centromeric Retrotransposons at Diploid and Allotetraploid Centromeric and Pericentromeric Regions.

Centromeric regions of plants are generally composed of large array of satellites from a specific lineage of LTR-retrotransposons, called Centromeric Retrotransposons. Repeated sequences interact with a specific H3 histone, playing a crucial function on kinetochore formation. To study the structure and composition of centromeric regions in the genus , we annotated and classified Centromeric Retrotransposons sequences from the allotetraploid genome and its two diploid ancestors: and .