Facial profile shape, malocclusion and palatal morphology in Malay obstructive sleep apnea patients.

Objective: To test the null hypothesis that there is no difference in facial profile shape, malocclusion class, or palatal morphology in Malay adults with and without obstructive sleep apnea (OSA).

Materials And Methods: Subjects were 120 adult Malays aged 18 to 65 years (mean +/- standard deviation [SD], 33.2 +/- 13.

Assessment of 3-D nasal airway morphology in Southeast Asian adults with obstructive sleep apnea using acoustic rhinometry.

The aim of the present study is to investigate nasal airway morphology in Asian adults with and without obstructive sleep apnea (OSA) using acoustic rhinometry (AR), principal components analysis (PCA), and 3-D finite-element analysis (FEA). One hundred eight adult Malays aged 18-65 years (mean ± SD, 33.2 ± 13.

Dental arch morphology in south-east Asian adults with obstructive sleep apnoea: geometric morphometrics.

The association between dental arch morphology and the aetiology of obstructive sleep apnoea (OSA) is not clear. To compare dental arch morphology in 108 Asian adults with and without ''OSA, overnight'' hospital polysomnography was performed, and sleep reports were obtained for all subjects. Standardized digital photographs were also taken of the subjects' upper and lower study models.

Craniofacial obesity in patients with obstructive sleep apnea.

Introduction: Obstructive sleep apnea (OSA) and obesity are serious, widespread public health issues.

Objective: To localize and quantify geometric morphometric differences in facial soft tissue morphology in adults with and without OSA.

Materials And Methods: Eighty adult Malays, consisting of 40 patients with OSA and 40 non-OSA controls, were studied.

Cranial base and airway morphology in adult malays with obstructive sleep apnoea.

Background: Obstructive sleep apnoea (OSA) has been described as a public health problem comparable to smoking in its impacts upon society.

Objective: To compare the differences in cranial base and airway morphology in Malay adults with and without OSA using finite element analysis (FEM).

Method: Lateral skull radiographs of 38 adult Malays aged 18-60 years were divided into two groups of 19 (13 male, 6 female).

Gene expression analysis of osteoblasts seeded in coral scaffold.

Coral matrix of Porites sp. has the suitable properties for bone cell growth. This study was aimed to study the gene expression levels of osteoblast specific genetic markers; RUNX2, osteopontin, alkaline phosphatase and osteocalcin from osteoblasts seeded in coral scaffold, which are important in determining the feasibility of osteoblasts.

In vitro cytotoxicity evaluation of biomaterials on human osteoblast cells CRL-1543; hydroxyapatite, natural coral and polyhydroxybutarate.

The aim of this study was to evaluate the in vitro cytotoxicity of biomaterials; Hydroxyapatite (HA), Natural coral (NC) and Polyhydroxybutarate (PHB). Three different materials used in this study; HA (Ca10(PO4)6(OH)2), NC (CaCO3) and PHB (Polymer) were locally produced by the groups of researcher from Universiti Sains Malaysia. The materials were separately extracted in the complete culture medium (100mg/ml) for 72h and introduced to the osteoblast cells CRL-1543.

Comparative study between dense and porous hydroxyapatite using light and scanning electron microscopy.

This in vivo study revealed that porous hydroxyapatite (PHA) and dense hydroxyapatite (DHA) are good implant materials that can accelerate bone healing and resorbed in acceptable time. But there were differences in the mechanism of the resorption of DHA and PHA due to variability in the physical properties and osteogenicity.

A comparative study of osseointegration phenomenon in coated and non-coated NiTi implants in a rabbit model.

There was a significant increased in Absolute Contact Length measurements of endosteal bone growth along the Nickel-Titanium (NiTi) implant coated with the natural coral powder and Hydroxyapatite (HA) compared to the non-calcium coated implants. This study demonstrated that coated implants seemed to show earlier and higher osseointergration phenomena compared to non coated ones. Furthermore, there was significantly greater bone-to-implant contact at the apical 1/3rd of the coated implants.

In vivo study of CORAGRAF: a preliminary results.

The main objective of the study was to determine the biodegradability, resorption and osteoconductivity potency of coral implant. Coral blocks (CORAGRAF) were prepared from sea coral Porites species. The blocks were implanted in the right mandible of rabbit model.

Mutagenicity of CORAGRAF and REKAGRAF in the Ames test.

Mutagenicity of CORAGRAF (natural coral) and REKAGRAF (hydroxyapatite) was tested in Ames test with and without an external metabolic activation system (S9). The test revealed no mutagenic activity of both locally produced osseous substitutes.

Objective assessment of nasal resistance in patients with nasal disease.

Nasal obstruction is a subjective complaint in patients with nasal disease. The ability to quantitate the nasal ventilation dysfunction would be useful for making the appropriate choice of nasal disease management. This cross-sectional study comprised of 200 adult subjects.

Active anterior rhinomanometry analysis in normal adult Malays.

The differences in facial anatomical structures of the major ethnic groups, may also be reflected in nasal resistance. Active anterior rhinomanometry (AAR) is the recommended technique for the objective assessment of nasal airway resistance (NAR). This study comprised of 85 adult Malay subjects.