Publications by authors named "Suzanne Wernke"
Article Synopsis
- This study aimed to explore the link between the severity of premenstrual syndrome (PMS) symptoms and headache severity during natural menstrual cycles and after medical oophorectomy treatment.
- Research showed that a significant percentage of individuals with menstrual migraines experienced PMS, but previous studies have rarely looked at their relationship.
- Analysis from a randomized-controlled trial indicated a strong correlation between PMS severity and headache severity, with the menstrual cycle influencing this association.
Objective: (1) To determine whether the attack characteristics of migraine differ between different intervals of the menstrual cycle; (2) To ascertain whether the "rate of change,""magnitude of change," or "total burden" of urinary hormone metabolites correlates with headaches outcome measures during different intervals of the menstrual cycle.
Background: The mechanisms through which migraines are influenced by ovarian hormones remain unclear. No previous studies until now have identified "hormonally defined" time intervals within the female menstrual cycle and compared headache outcome measures among these intervals in female migraineurs.
Objectives: To determine the preventive benefit of "medical oophorectomy" and transdermal estradiol in women with migraine.
Background: Epidemiological studies have demonstrated that declines in serum estrogen levels occurring during normal menstrual cycles can trigger headache in women with migraine. Prior to this study, no randomized controlled trials have evaluated whether minimizing these hormonal changes pharmacologically can prevent headache.