Publications by authors named "Suzanne Ratsimamanga-Urverg"
Croton kimosorum Leandri is an endemic species to Madagascar. The chemical composition of aerial parts, leaf and stem oils is reported for the first time. Analysis was carried out by combination of chromatographic (CC, GC), spectroscopic and spectrometric (MS, 13C NMR) techniques.
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- The study analyzed volatile compounds from the leaves of the Madagascar endemic plant Vepris madagascarica using various chemical techniques like GC, GC-MS, and 13C NMR spectroscopy.
- The main component identified in the oil samples was (E)-anethole, comprising about 78% of the composition, followed by estragole.
- The trunk bark oil also featured (E)-anethole as its primary component (84.6%), along with smaller amounts of sesquiterpenes.
One hundred and ninety plants, of which 51 are used to treat malaria in traditional medicine, were collected in five different ecosystems of Madagascar for a screening programme devoted to the search of naturally-occurring antimalarial compounds. Thirty-nine plants, of which 12 are used as herbal antimalarials, were found to display in vitro activity against Plasmodium falciparum with a median inhibitory concentration (IC50) lower than 5 microg/ml while 9 had an IC50 ranging from 5 to 7.5 microg/ml.
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