Publications by authors named "Suzanne Nijhuis"
Adv Healthc Mater
October 2024
Article Synopsis
- Transplantation of microencapsulated pancreatic cells offers a new treatment for type 1 diabetes (T1DM) by protecting β-cells from immune response, reducing the need for continuous immunosuppression.
- The article introduces a novel method to create semi-permeable, non-immunogenic polyethylene glycol-tyramine (PEG-TA) microgels that encapsulate β-cells, allowing them to form islet-sized structures and maintain function.
- Results show that these microgels provide effective immunoprotection and allow β-cells to remain viable and responsive to glucose, successfully restoring normal blood sugar levels in diabetic mice after transplantation.
