Publications by authors named "Suzanne Neil"
Article Synopsis
- Ashkenazi Jewish people have a higher likelihood of carrying pathogenic variants related to cancer, with three specific mutations accounting for over 90% of cases; traditional cancer history-based testing often fails to identify a significant number of these individuals.
- A study compared two different screening programs in Australia: one using an online tool in Sydney and the other using in-person sessions in Melbourne, testing 2167 Jewish participants for the mutations.
- Results indicated that both programs were well-received, successfully identifying several individuals with mutations who might otherwise have gone undetected; overall satisfaction was high, and knowledge about the risks was good, despite some slight anxiety and distress reported by those with mutations.
Introduction: People of Ashkenazi Jewish (AJ) ancestry are more likely than unselected populations to have a pathogenic variant, which cause a significantly increased risk of breast, ovarian and prostate cancer. Three specific pathogenic variants, referred to as -Jewish founder mutations (B-JFM), account for >90% of pathogenic variants in people of AJ ancestry. Current practice of identifying eligible individuals for testing based on personal and/or family history has been shown to miss at least 50% of people who have one of these variants.
View Article and Find Full Text PDFBreast cancer and its treatment in reproductive-age women can reduce fertility and compromise family formation. To learn about women's experiences of fertility-related cancer care we interviewed 10 women (aged 26-45), at least one year postdiagnosis. Thematic analysis revealed that all women, including one who chose to be child-free, valued fertility and motherhood.
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