Publications by authors named "Suzanne Meiring"
Article Synopsis
- * The study included 14 patients on insulin, where ReCET was performed with optimized electroporation doses, and patients were switched to a glucagon-like peptide 1 receptor agonist afterwards.
- * Results indicated that ReCET was safe and effective, with 86% of patients remaining off insulin after 12 months and showing significant improvements in their blood sugar levels.
Background And Aims: The duodenum has been shown to play a key role in glucose homeostasis. Duodenal mucosal resurfacing (DMR) is an endoscopic procedure for patients with type 2 diabetes (T2D) in which the duodenal mucosa is hydrothermally ablated. DMR improves glycemic control, but the underlying mechanisms remain unclear.
View Article and Find Full Text PDFArticle Synopsis
- The gut microbiota plays a crucial role in how our bodies metabolize nutrients and manage digestion, with new procedures like Duodenal Mucosal Resurfacing (DMR) showing promise in improving metabolic health for patients with type 2 diabetes.
- In a study, 69% of insulin-dependent type 2 diabetes patients discontinued insulin treatment after undergoing DMR combined with a glucagon-like peptide-1 receptor agonist, leading to better blood sugar control.
- Analysis of gut microbiota showed correlations between changes in diversity and metabolic health outcomes, but no significant diversity changes were found within three months, indicating that further research is needed to understand these relationships better.
Duodenal mucosal resurfacing (DMR) is a new endoscopic ablation technique aimed at improving glycemia and metabolic control in patients with type 2 diabetes mellitus (T2DM). DMR appears to improve insulin resistance, which is the root cause of T2DM, but its mechanism of action is largely unknown. Bile acids function as intestinal signaling molecules in glucose and energy metabolism via the activation of farnesoid X receptor and secondary signaling [e.
View Article and Find Full Text PDFBackground And Aims: Duodenal mucosal resurfacing (DMR) is an endoscopic intervention in which the duodenal mucosa is ablated by hydrothermal energy. DMR improves glycemic control in patients with type 2 diabetes (T2D), most likely by altered duodenal signaling leading to insulin sensitization. We studied whether we could discontinue insulin use in T2D patients by combining DMR with glucagon-like peptide-1 receptor agonist (GLP-1RA) and lifestyle counseling.
View Article and Find Full Text PDFUnlabelled: This study aims to provide an overview of both our own experience and the available literature on the treatment of post-appendectomy abscess (PAA) in children. We performed a historical cohort study encompassing all children aged 0-17 years old treated for a radiologically confirmed PAA between 2007 and 2013. Their medical charts were reviewed and descriptive analyses were performed.
View Article and Find Full Text PDF