Objectives: The aim of this study was to explore the clinical factors associated with the development of cystic fibrosis-associated liver disease (CFALD).
Study Design: This was a case-control study of all children (age 5-18 years) with established CFALD in the Republic of Ireland between January 1999 and June 2000. Each child was pair matched for age and sex with a patient with cystic fibrosis (CF) without evidence of liver disease.