Synopsis of recent research by authors named "Suzanne J Hodgkinson"
- Suzanne J Hodgkinson's research primarily focuses on the role of T regulatory cells in transplantation and autoimmunity, particularly their mechanisms for inducing tolerance to allografts and their dynamics in autoimmune conditions like multiple sclerosis.
- Her studies have highlighted the heterogeneity of CD4CD25 T regulatory cells, revealing the distinct subpopulations that contribute to transplant tolerance and autoimmune inhibition, such as Thymus-derived Tregs and antigen-specific subsets.
- Additionally, Hodgkinson's work emphasizes the impact of specific cytokines, like IL-5, on the survival and activation of these regulatory cells, proposing new therapeutic approaches to enhance transplant tolerance and mitigate autoimmune diseases.
