The effect of gender on outcomes of aortoiliac artery interventions for claudication.

Objective: To explore the relationship between gender, native artery diameters, and outcomes of stent revascularization (ST) in the "Claudication: Exercise versus Endoluminal Revascularization" trial.

Methods: A comparative analysis was performed of the impact of gender, age, weight, height, body mass index, and body surface area on revascularization outcomes at baseline and 6months in 55 arterial segments of aorta, common iliac artery, and external iliac artery (EIA).

Results: Women demonstrated smaller diameter of the EIA.

A randomized trial of therapies for type 2 diabetes and coronary artery disease.

Background: Optimal treatment for patients with both type 2 diabetes mellitus and stable ischemic heart disease has not been established.

Methods: We randomly assigned 2368 patients with both type 2 diabetes and heart disease to undergo either prompt revascularization with intensive medical therapy or intensive medical therapy alone and to undergo either insulin-sensitization or insulin-provision therapy. Primary end points were the rate of death and a composite of death, myocardial infarction, or stroke (major cardiovascular events).