Publications by authors named "Suzanne Birmingham"

Tertiary syphilis may present a diagnostic challenge due to negative nontreponemal serologies in up to 30% of cases and frequent lack of identifiable spirochetes on histopathology or other direct detection tests. We report 2 cases of round bodies staining with Treponema pallidum immunohistochemistry by light microscopy in biopsies from cutaneous syphilitic gummata. In 1 case, the finding was validated 3 times by 2 independent laboratories; in the other case, T.

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Complete scalp hair loss can be a source of distress for affected children and their families. In addition to infectious and trauma-related causes of hair loss, infants and children may present with total scalp alopecia arising from a range of genetic predispositions. Our objective with this review was to identify the common genetic conditions in children with complete scalp alopecia.

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Article Synopsis
  • * A biopsy revealed findings indicative of lichen spinulosus, a skin condition that has not been previously reported in patients recovering from TEN.
  • * Treatment with ammonium lactate 12% lotion led to improvement, highlighting the importance for healthcare providers to recognize potential skin issues after TEN for better patient counseling.
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Primary erythromelalgia, while uncommon, may significantly decrease the quality of life of those affected. While many patients with erythromelalgia require systemic therapy, there is no standard of care for this condition. Herein, we report a 7-year-old girl who experienced resolution of erythromelalgia symptoms with no adverse effects after treatment with low-dose gabapentin.

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Article Synopsis
  • A 70-year-old woman developed a painful, enlarging nodule on her forearm, which was found to be a subcutaneous mass after surgical excision.
  • The pathology revealed that it was an intravenous lobular capillary hemangioma (IVLCH), a rare benign tumor that typically causes discomfort but can be cured with excision.
  • The authors propose a new acronym for identifying various cause of tender skin tumors, emphasizing the need for ongoing updates in this classification to assist medical professionals in their diagnoses.*
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Enfortumab vedotin is an antibody-drug conjugate used for treatment of urothelial cancer. It has recently been associated with several reports of Stevens Johnson syndrome/toxic epidermal necrolysis (TEN). In this report, we describe the case of a 63-year-old man who developed widespread, near full-thickness desquamation, clinically mimicking TEN but with histologic features of toxic erythema of chemotherapy.

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