Publications by authors named "Suzan Sweitat"
Article Synopsis
- Ataxia-telangiectasia (A-T) is a genetic disorder caused by mutations in the ATM gene, resulting in symptoms like progressive ataxia, immunodeficiency, and increased cancer risk.
- Researchers hypothesize that the degeneration of cerebellar cells in A-T is linked to specific vulnerabilities of cerebellar microglia, the immune cells in the brain.
- Their findings indicate that microglia from A-T affected mice show impaired functions such as phagocytosis and neurotrophic factor secretion, highlighting the critical roles of these cells in the disease's progression.
