A novel sponge-like composite biosorbent fabricated by sodium alginate and polyethyleneimine for uranium(VI) extraction from seawater.

Uranium extraction from seawater (UES) has important strategic significance for maintaining the sustainable development of nuclear energy. This article presents the preparation of a low-cost, efficient, and highly reusable biosorbent sodium alginate/polyethyleneimine (SA/PEI) through a simple one-step crosslinking process. The chemical crosslinking between PEI and SA provides biosorbent excellent mechanical strength and thermal stability.

and Studies of Metabolic Activation of Marrubiin, a Bioactive Constituent from .

Marrubiin, a furanoid compound, is a well-known diterpenoid lactone isolated from , which displays a wide spectrum of pharmacological effects and potential hepatotoxicity. Considering that marrubiin contains a structural alert, furan ring, metabolic activation may be one of the major metabolic pathways, and the reactive metabolite may be involved in the hepatotoxicity. The present study was carried out to investigate the bioactivation mechanism of marrubiin in rats and humans.

Silibinin suppresses epithelial-mesenchymal transition in human non-small cell lung cancer cells by restraining RHBDD1.

Background: Rhomboid domain containing 1 (RHBDD1) plays a crucial role in tumorigenesis. Silibinin, which is a natural extract from milk thistle, has shown anti-tumor effects against various tumors. Here, we investigate whether silibinin affects the function of RHBDD1 in non-small cell lung cancer (NSCLC) cell proliferation, migration and invasion.