Publications by authors named "Suvrendu Sankar Kar"
Modulatory role of miRNAs in thyroid and breast cancer progression and insights into their therapeutic manipulation.
Curr Res Pharmacol Drug Discov
October 2022
Over the past few decades, thyroid cancer has become one of the most common types of endocrine cancer, contributing to an increase in prevalence. In the year 2020, there were 586,202 newly diagnosed cases of thyroid cancer around the world. This constituted approximately 3.
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- In November 2021, the Omicron variant of SARS-CoV-2 was detected in South Africa, leading the WHO to classify it as a variant of concern due to its rapid spread and ability to evade immunity.
- Omicron has over 60 mutations and its sub-lineages (BA.1.1, BA.2, BA.3) exhibit additional changes, resulting in this variant causing less severe illness compared to Delta but still posing risks to the unvaccinated.
- A debate is ongoing among scientists about Omicron's potential role as a natural vaccine, with some arguing that it might boost immunity similarly to live attenuated vaccines, while others warn of its significant health risks.
Article Synopsis
- SARS-CoV-2, the virus causing COVID-19, emerged in December 2019, leading the WHO to declare a pandemic in March 2020 due to its rapid spread.
- India launched its vaccination campaign against SARS-CoV-2 on January 13, 2021, administering two vaccines: Covaxin, made with inactivated viral particles, and Covishield, an adenovirus vector-based vaccine.
- Covishield has shown around 90% effectiveness while Covaxin is about 80% effective; both have been effective against mutant variants, although Covaxin may provide broader protection if future variants alter the structure of the virus's spike protein.
Article Synopsis
- The study focused on COVID-19 vaccine acceptance in West Bengal, India, highlighting vaccine hesitancy as a significant obstacle.
- An online survey of 803 respondents revealed that while a majority expressed willingness to get vaccinated, a notable percentage still doubted the necessity of vaccination.
- Results indicated that misinformation and lack of awareness, rather than hesitancy, could be the biggest challenges affecting vaccination rates in the region.
Herpes zoster is a unilateral painful vesicular cutaneous eruption caused by the reactivation of the Varicella zoster virus. It commonly affects the older people and immunocompromised individuals. The dermatomes from T3 to L3 are most frequently involved.
View Article and Find Full Text PDFA young Indian man presented with nine-month history of chronic diarrhea, occasionally mixed with blood and intermittent colicky abdominal pain. He also complained of generalized body swelling for the last three months. On examination, he had diffuse hyperpigmentation of the skin and dystrophic nail changes.
View Article and Find Full Text PDFWe are presenting two cases of Guillain-Barré syndrome where it is preceded by hepatitis E virus (HEV) and Japanese encephalitis virus (JEV) infection, respectively. Our first case is a forty-three-year-old nondiabetic, nonhypertensive female who was initially diagnosed with acute HEV induced viral hepatitis and subsequently developed acute onset ascending quadriparesis with lower motor neuron type of bilateral facial nerve palsies and respiratory failure. Second patient was a 14-year-old young male who presented with meningoencephalitis with acute onset symmetric flaccid paraparesis.
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