Publications by authors named "Suvin Park"

Article Synopsis
  • Europe, the U.S., and Korea each have systems to track rare adverse events from drugs after they are marketed, with Korea focusing on a re-examination system and risk management plan to monitor safety.
  • This study compares post-marketing safety issues related to the drug dapagliflozin as identified by the European Medicines Agency (EMA), the U.S. FDA, and the Korean Ministry of Food and Drug Safety.
  • There is a 71% agreement between safety issues found by the EMA/FDA and those noted in Korea, but Korea's system struggles with long-term outcome tracking and needs better regulations and guidelines for ongoing safety assessments.
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Background: Roots perform multifaceted functions in plants such as movement of nutrients and water, sensing stressors, shaping microbiome, and providing structural support. How roots perceive and respond above traits at the molecular level remains largely unknown. Despite the enormous advancements in crop improvement, the majority of recent efforts have concentrated on above-ground traits leaving significant knowledge gaps in root biology.

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Background: Diphtheria-tetanus-acellular pertussis, polio, and Haemophilus influenza type B (DTaP-IPV/Hib) combination vaccine was introduced as a part of the Korea National Immunization Program (NIP) on June 19, 2017. Combination vaccines can improve vaccination rates by simplifying the vaccination schedule.

Objective: To explain how the introduction of DTaP-IPV/Hib in the NIP has changed vaccination practices for infants.

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Background: How plants emit, perceive, and respond to sound vibrations (SVs) is a long-standing question in the field of plant sensory biology. In recent years, there have been numerous studies on how SVs affect plant morphological, physiological, and biochemical traits related to growth and adaptive responses. For instance, under drought SVs navigate plant roots towards water, activate their defence responses against stressors, and increase nectar sugar in response to pollinator SVs.

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Mechanosensitive channels are integral membrane proteins that rapidly translate extrinsic or intrinsic mechanical tensions into biological responses. They can serve as potential candidates for developing smart-resilient crops with efficient root systems. Mechanosensitive (MS) calcium channels are molecular switches for mechanoperception and signal transduction in all living organisms.

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Soil flooding has emerged as a serious threat to modern agriculture due to the rapid global warming and climate change, resulting in catastrophic crop damage and yield losses. The most detrimental effects of waterlogging in plants are hypoxia, decreased nutrient uptake, photosynthesis inhibition, energy crisis, and microbiome alterations, all of which result in plant death. Although significant advancement has been made in mitigating waterlogging stress, it remains largely enigmatic how plants perceive flood signals and translate them for their adaptive responses at a molecular level.

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Plants are very often confronted by different heavy metal (HM) stressors that adversely impair their growth and productivity. Among HMs, chromium (Cr) is one of the most prevalent toxic trace metals found in agricultural soils because of anthropogenic activities, lack of efficient treatment, and unregulated disposal. It has a huge detrimental impact on the physiological, biochemical, and molecular traits of crops, in addition to being carcinogenic to humans.

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