Phytochemical Investigation and Biological Activities of Extract as Anti-Tyrosinase: Isolation of Natural Compounds, and Study.

Tyrosinase is an important enzyme in the biosynthesis of melanin. Many skin-whitening agents that inhibit tyrosinase activity from natural sources have been identified because they are harmless and non-toxic. In this work, 114 samples of 54 Fabaceae plants were assessed for their anti-tyrosinase activity using a dopachrome method.

Comparative efficacy of extract delivery PEG--PCL, niosome, and their combination against genotype T4: characterization, inhibition, anti-adhesion, and cytotoxic activity.

Background: spp. is a waterborne, opportunistic protozoan that can cause amebic keratitis and granulomatous amebic encephalitis. is a native tree in Malaysia, and its extracts possess a broad range of biological activities.

Inhibitory and anti-adherent effects of L. leaf extract against in co-infection with and : A sustainable one-health approach.

Background And Aim: Keratitis is a serious ocular infection often caused by pathogenic microorganisms such as spp. Among other harmful microbes, keratitis presents a particular challenge due to its resistance to conventional antimicrobial agents. Linn.

A Comparative Study of Chemical Profiling and Bioactivities between Thai and Foreign Hemp Seed Species ( L.) Plus an In-Silico Investigation.

Hemp ( L.) is a plant widely used by humans for textiles, food, and medicine. Thus, this study aimed to characterize the chemical profiling of 12 hemp seed extracts from Thai (HS-TH) and foreign (HS-FS) samples using gas chromatography-mass spectrometry (GC-MS).

Antibacterial and antivirulence factor activities of protein hydrolysates from Phatthalung Sangyod rice ( L.) seeds against zoonotic and foodborne pathogens.

Background And Aim: Antimicrobial resistance is an emerging public health threat. Foodborne illnesses are typically caused by bacteria, such as , , , and , which are frequently resistant to common antimicrobial agents. Rice is a staple grain in most parts of the world.

extract and its application in bovine teat dipping solution inhibit and eliminate biofilms in bovine mastitis-inducing staphylococci.

Background And Aim: Staphylococci, including , , and , are significant bacteria that induce bovine mastitis, primarily because they can form biofilms in bovine teat canals. This study aimed to investigate the efficacy of extract and a bovine teat dipping solution containing extract (BSP) against these mastitis-causing staphylococci.

Materials And Methods: BSP was prepared using extract as the bioactive compound.

Virulence factors and quorum sensing as targets of new therapeutic options by plant-derived compounds against bacterial infections caused by human and animal pathogens.

The emergence of antibiotic-resistant bacteria and hospital-acquired bacterial infection has become rampant due to antibiotic overuse. Virulence factors are secondary to bacterial growth and are important in their pathogenesis, and therefore, new antimicrobial therapies to inhibit bacterial virulence factors are becoming important strategies against antibiotic resistance. Here, we focus on anti-virulence factors that act through anti-quorum sensing and the subsequent clearance of bacteria by antimicrobial compounds, especially active herbal extracts.

Targeting proteins interaction with flavonoids of Propolis extract by and studies for promising therapeutic effects.

Propolis is a natural resinous mixture produced by bees. It provides beneficial effects on human health in the treatment/management of many diseases. The present study was performed to demonstrate the anti- activity of ethanolic extracts of Propolis samples from Iran.

Anti- activity of a semi-synthetic mangostin derivative and its ability in removal of WU19001 on contact lens.

L., also known as the mangosteen tree, is a native medicinal plant in Southeast Asia having a wide variety of pharmacologically active compounds, including xanthonoid mangostin. In this study, we examined the pharmacological activities of the selected semi-synthetic mangostin derivative, namely, amoebicidal activity, encystation inhibition, excystation activity, and removal capacity of adhesive from the surface of contact lens (CL).

Sangyod rice bran extract enhances growth during the exponential phase and antibacterial activity of supernatant against zoonotic and foodborne pathogens.

Background And Aim: Prebiotics are a group of nutrients or compounds that are degraded by the gut microbiota, including . The probiotic plays an important role in adhesion to the gut and is able to produce antimicrobial substances to inhibit pathogens. This study aimed to investigate the effects of Sangyod rice bran extract on the growth promotion of .

Robusta coffee extracts inhibit quorum sensing activity in and reduce biofilms against and .

Background And Aim: and cause foodborne intoxication in humans and animals. Pathogens can produce biofilms controlled by the quorum sensing system. The study aimed to investigate the antibacterial, antibiofilm, and anti-quorum sensing activities of P.

Knema retusa is antibacterial and antibiofilm against antibiotic resistant Staphylococcus aureus and S. haemolyticus isolated in bovine mastitis.

This study aimed to assess antibacterial activity of Knema retusa wood extract (KRe) against antibiotic resistant staphylococci which are causative agents of bovine mastitis. From 75 cases of intramammary infections in dairy cows, 66 staphylococcal isolates were collected, including 11 Staphylococcus aureus isolates (17%) and 55 coagulase-negative staphylococci (83%). Sixty isolates (91%) formed strong biofilms.

Curcumin effect on encystation under nutrient starvation.

Background: Curcumin is an active compound derived from turmeric, , and is known for its benefits to human health. The amoebicidal activity of curcumin against was recently discovered. However, a physiological change of intracellular pathways related to encystation mechanism, including autophagy in the surviving amoeba after curcumin treatment, has never been reported.

Antibacterial, antibiofilm, and anti-adhesion activities of Piper betle leaf extract against Avian pathogenic Escherichia coli.

Piper betle leaves have traditionally been used to treat many diseases, including bacterial infections. The present study aimed to investigate the antibacterial, antibiofilm, and anti-adhesion activities of P. betle extract against avian pathogenic Escherichia coli (APEC).

Phytochemical, anti-Acanthamoeba, and anti-adhesion properties of Garcinia mangostana flower as preventive contact lens solution.

Acanthamoeba keratitis infection extends due to the growing number of contact lens users. Indigenous plants including Garcinia mangostana play a vital role in human health and well being. Many species of this plant have been reported with myriads of potent medicinal properties.

Extract Has Antiamoebic Activity to Trophozoites and Changes Expression of Autophagy-Related Genes.

, a well-known medicinal plant, has been used for several therapeutic purposes as it contains numerous pharmacological active compounds. Our study reported an anti-parasitic activity of seed extract against . The stress induced by the extract on the surviving trophozoites for encystation and vacuolization was examined by microscopy, and transcriptional expression of autophagy-related genes was investigated by quantitative PCR.

Potential anti- and anti-adhesion activities of and extracts and their synergistic effects in combination with chlorhexidine against trophozoites and cysts.

Plants with medicinal properties have been used in the treatment of several infectious diseases, including infections. The medicinal properties of Cambodian plant extracts; and were investigated against . A total of 39 plant extracts were evaluated and, as a result, 22 extracts showed positive anti- activity.

Amoebicidal activity of extract and its effect on autophagy-related gene expression at the transcriptional level.

Cassia angustifolia Vahl. plant is used for many therapeutic purposes, for example, in people with constipation, skin diseases, including helminthic and parasitic infections. In our study, we demonstrated an amoebicidal activity of C.

Anti-Acanthamoeba synergistic effect of chlorhexidine and Garcinia mangostana extract or α-mangostin against Acanthamoeba triangularis trophozoite and cyst forms.

Acanthamoeba spp. can cause amoebic keratitis (AK). Chlorhexidine is effective for AK treatment as monotherapy, but with a relative failure on drug bioavailability in the deep corneal stroma.

Curcuma longa rhizome extract and Curcumin reduce the adhesion of Acanthamoeba triangularis trophozoites and cysts in polystyrene plastic surface and contact lens.

Curcuma longa and Curcumin have been documented to have a wide spectrum of pharmacological effects, including anti-Acanthamoeba activity. Hence, this study sought to explore the anti-adhesion activity of C. longa extract and Curcumin against Acanthamoeba triangularis trophozoites and cysts in plastic and contact lenses.

Gordonia sediminis sp. nov., an actinomycete isolated from mangrove sediment.

The taxonomic position of an actinomycete designated AMA 120, isolated from mangrove sediment, was clarified by phenotypic, chemotaxonomic and phylogenetic studies. The 16S rRNA gene sequence revealed that strain AMA 120 was most closely related to Gordonia rhizosphera NBRC 16068 (98.9 %), Gordonia polyisoprenivorans NBRC 16320 (98.

Evaluation of antibacterial potential of mangrove sediment-derived actinomycetes.

Actinomycetes are well-known as the source of bioactive metabolites. In this work, 16 out of 118 (13.6%) isolates of mangrove sediment-derived actinomycetes showed potential antibacterial activity against at least one bacterial strain.